BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Peripheral benzodiazepine receptor (TSPO; PBR); Mdm2 p53 binding protein homolog (MDM2; HDM2)

May 12, 2016 7:00 AM UTC

In vitro studies identified an inhibitor of MDM2/p53 binding and TSPO that could help treat glioblastoma. Chemical synthesis and in vitro testing of 2-phenylindolylglyoxylyl dipeptides identified a co...