ARTICLE | Distillery Therapeutics
Therapeutics: E1A binding protein p300 (EP300; p300); CREB binding protein (CREBBP; CBP)
March 31, 2016 7:00 AM UTC
Cell culture and mouse studies suggest inhibiting EP300 could help treat CREBBP-deficient cancers. In a human CREBBP-deficient lung cancer cell line, siRNA targeting EP300 decreased viability and prol...