Knowing when to fold
How unfolded protein stress plays a common role in Type I and II diabetes
A team from the Flanders Institute for Biotechnology (VIB) has linked two genes involved in the unfolded protein stress response to the fragility of pancreatic β cells involved in both Type I and Type II diabetes, and developed a mouse model that could provide a new tool for identifying drugs for both forms of the disease.
While Type I diabetes involves autoimmune
