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Redefining the pathogen defense

Phagocytosis - the process by which macrophages and neutrophils engulf and destroy pathogens - has been thought to occur through use of the cells' plasma membranes. But work published in Cell by Caprion Pharmaceuticals Inc. founder Michel Desjardins shows that the macrophage's endoplasmic reticulum (ER) is responsible for phagocytosis, meaning that neutrophils and macrophages do their

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