BioCentury
ARTICLE | Emerging Company Profile

RaNA: Specific in epigenetics

Arthur Krieg, Jeannie Lee, Atlas Ventures found epigenetics company RaNA

January 23, 2012 8:00 AM UTC

Most epigenetics companies aim to globally inhibit regulatory proteins, such as histone methyltransferases or histone demethylases, which may affect thousands of genes. RaNA Therapeutics Inc. is instead targeting long non-coding RNA, or lncRNA, to up-regulate gene expression in a locus-specific fashion. This could give it a specificity advantage over other epigenetic approaches.

RaNA was founded in 2011 after Atlas Venture's Jean-Francois Formela saw the potential to form a company based on Jeannie Lee's work at Massachusetts General Hospital...