To include your compound in the COVID-19 Resource Center, submit it here.

Exelixis makes its case

Exelixis argues for novel Phase III strategy for cabozantinib in prostate cancer

New Phase II data for Exelixis Inc.'s cabozantinib and Phase III plans for the cancer candidate spooked investors last Monday, as the stock lost 20% of its value. But on a post-market investor briefing, the company attempted to put the six deaths in the trial into perspective and offered buy-in from KOLs on its plans to get approval in castration-resistant prostate cancer using a novel composite endpoint.

The stock rebounded 12% on Tuesday, before settling back to close the week with a 16% loss.

The next step is firming up plans for the composite endpoint study with FDA, which Exelixis hopes will provide a quicker path to approval than the other Phase III trials it has planned.

As reported at the

Read the full 1187 word article

Trial Subscription

Get a two-week free trial subscription to BioCentury

SIGN UP

Article Purchase

This article may not be distributed to non-subscribers
More Info >PURCHASE