Novira: Capsid counterattack
Novira developing therapeutics against viral capsids for HBV, HIV
Developing compounds against viral capsids is an attractive therapeutic strategy in theory, but has yet to work in practice because of the difficulty of inhibiting protein-protein interactions. Novira Therapeutics Inc. believes it has the right medicinal chemistry capabilities to develop small molecules that prevent capsid formation in HBV and HIV.
The capsid is a protein shell that forms around a virus to protect it during passage from one cell to another. "They do not have obvious binding sites, so there was