Two legs to stand on

The failure of its daclizumab antibody in ulcerative colitis last week removes a leg from the platform Protein Design Labs Inc. is building in inflammatory bowel disease. With two legs of its IBD platform remaining - Nuvion anti-CD3 antibody and HuZaf fontolizumab, a humanized antibody targeting interferon (IFN) gamma - PDLI says it will stick with the disease area.

However, the failure also means that any upside from the $80 million PDLI paid upfront to reacquire rights to daclizumab

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