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ARTICLE | Emerging Company Profile

PanOptica: Dropping in on VEGF

PanOptica VEGF receptor inhibitor avoids the needle for wet AMD

January 10, 2011 8:00 AM UTC

Most of the next generation of treatments for age-related macular degeneration are focusing on reducing or eliminating intravitreal injections, which are burdensome to patients and present safety risks. PanOptica Inc. believes its PAN-90806, a small molecule selective inhibitor of VEGF receptor, will be among the best approaches because it has a validated mechanism, is formulated as an easy-to-use eyedrop and has high bioavailability at the disease site.

Last week, PanOptica raised $30 million in a series A round and licensed exclusive, worldwide rights to PAN-90806 for ophthalmic diseases from OSI Pharmaceuticals Inc., a subsidiary of Astellas Pharma Inc...