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Glycart: 'Effect'-ing function

The binding of an antibody to an antigen often has no direct biological effect. Rather, the significant biological effects are a consequence of secondary "effector functions" of antibodies, such as Fc binding affinity and antibody-dependent cellular cytotoxicity (ADCC), which is mediated by Fc binding. Indeed, many antibodies never make it through clinical development because they don't have good effector function. Glycart Biotechnology AG

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