ARTICLE | Cover Story
EGFR's New Tricks
May 15, 2008 7:00 AM UTC
A pair of cell culture studies suggests that epidermal growth factor receptor
promotes cancer through mechanisms beyond kinase activity. According to company representatives and researchers contacted by SciBX, the findings point to new ways of boosting the efficacy of approved drugs that target epidermal growth factor receptor-small molecule tyrosine kinase inhibitors and mAbs. However, the results must be validated with further studies in human tumors...