BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Cyclin dependent kinase 8 (CDK8); cyclin C (CCNC)

October 22, 2015 7:00 AM UTC

In vitro, cell culture and mouse studies identified cortistatin A as an inhibitor of the CDK8-CCNC interaction that could help treat leukemia. In vitro, cortistatin A bound the CDK8-CCNC complex with ...