BioCentury
ARTICLE | Distillery Techniques

Techniques: A knock-in, knockout, transgenic mouse model of moderate spinal muscular atrophy (SMA)

November 19, 2015 8:00 AM UTC

A mouse model of moderate SMA could be useful for testing therapies administered long after disease onset. The mouse model was generated via knockout of one mouse survival of motor neuron 1 telomeric ...