BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Histone deacetylase (HDAC); runt-related transcription factor 3 (RUNX3)

April 16, 2015 7:00 AM UTC

In vitro and rodent studies suggest HDAC inhibitors that activate the tumor suppressor RUNX3 could help treat cancer. Chemical synthesis and testing in an HDAC inhibition-induced RUNX3 activation assa...