BioCentury
ARTICLE | Distillery Therapeutics

Therapeutics: Baculoviral IAP repeat-containing 2 (BIRC2; cIAP1); X-linked inhibitor of apoptosis (XIAP)

April 2, 2015 7:00 AM UTC

In vitro and mouse studies identified a macrocylic antagonist of cIAP1 and XIAP that could help treat cancer. In vitro screening of a cyclic peptidomimetic library identified a lead compound that inhi...