Extracting PD therapy from coffee

A U.S. team that included researchers from Signum Biosciences Inc. has identified a small molecule in coffee that increased motor function in a mouse model of Parkinson's disease.¹ By blocking disease progression, the compound may be superior to marketed PD drugs that only improve symptoms.

The Signum-led group now will use a $295,000 grant from The Michael J. Fox Foundation for Parkinson's Research to develop the compound-and others acting via the same mechanism-to treat PD...