BioCentury
ARTICLE | Cover Story

Cardiotrophin workout

August 25, 2011 7:00 AM UTC

A team at the University of Navarrahas shown that obesity and metabolic syndrome can be treated with cardiotrophin-1, a cytokine that regulates energy utilization and appetite.1 The findings open up a new indication for university spinout Digna Biotech S.L., which is developing the cytokine as a cytoprotective agent in liver transplantation.

Cardiotrophin-1 (CT-1) is a member of the IL-6 family of cytokines. According to Jesús Prieto, the compound "drew our attention about eight years ago because of its cytoprotective activitiesin hepatic indications."...