BioCentury
ARTICLE | Tools & Techniques

More iPS cells in less time

October 29, 2009 7:00 AM UTC

A team at The Scripps Research Institute has found that a trio of small molecules can provide more than a 200-fold boost in the generation of induced pluripotent stem cells from human fibroblasts while cutting the generation time in half.1

Fate Therapeutics Inc. has exclusively licensed the associated technology. Coupled with IP for an earlier fibroblast reprogramming protocol that only uses recombinant proteins,2 which the biotech also obtained from Scripps, the company hopes to use the technologies to generate pharmaceutical-grade induced pluripotent stem (iPS) cells for therapeutic use and drug discovery on an industrial scale...