BioCentury
ARTICLE | Targets & Mechanisms

More mileage out of myelin

January 6, 2011 8:00 AM UTC

A team led by U.K. researchers has shown that retinoid X receptor

agonists can enhance remyelination of demyelinated axons in rodents by increasing the differentiation of oligodendrocyte precursor cells into oligodendrocytes.1 This remyelination activity could spark interest in repurposing the agonists, which are on the market and in the clinic for cancer...