ARTICLE | Cover Story
A new spin on protegrin
March 4, 2010 8:00 AM UTC
Researchers at the University of Zurich and Polyphor Ltd. have developed protein epitope mimetics of the antimicrobial peptide protegrin I
that specifically target Pseudomonas aeruginosa via a mechanism of action that is distinct from the membrane-disrupting activity of the parent compound.1 The biotech expects its lead mimetic to enter Phase I ...