BioCentury
ARTICLE | Cover Story

A new spin on protegrin

March 4, 2010 8:00 AM UTC

Researchers at the University of Zurich and Polyphor Ltd. have developed protein epitope mimetics of the antimicrobial peptide protegrin I

that specifically target Pseudomonas aeruginosa via a mechanism of action that is distinct from the membrane-disrupting activity of the parent compound.1 The biotech expects its lead mimetic to enter Phase I ...