BioCentury
ARTICLE | Strategy

DREAM team

May 9, 2013 7:00 AM UTC

The DREAM Project has teamed up with Sage Bionetworks and announced four open challenges in computational biology that tackle issues relevant to drug discovery and development, including prediction of drug responses. The publication of results from their first collaboration on improving breast cancer prognosis provides a case study for the team's approach.1,2

DREAM-Dialogue on Reverse Engineering Assessment and Methods-was founded in 2006 by Gustavo Stolovitzky and Andrea Califano to organize open challenges aimed at improving computational biology. DREAM is sponsored by Columbia University, the NIH, IBM Corp. and The New York Academy of Sciences. Past challenges have tackled problems ranging from predicting drug sensitivity of cancer cell lines to modeling epitope-antibody interactions...