Finding the repurpose

A Stanford University team has used a computational approach to analyze publicly available gene expression profiles and identified two drug repurposing opportunities.^1,2 The researchers found that the anticonvulsant topiramate could have use in inflammatory bowel disease and that the generic ulcer drug cimetidine could help treat lung adenocarcinoma.

The computational method is exclusively licensed to NuMedii Inc., a bioinformatics spinout from Stanford that is using the technology to evaluate molecular data to repurpose drugs...