BioCentury
ARTICLE | Clinical News

Paradigm Biosciences Inc. preclinical data

October 28, 1996 8:00 AM UTC

Paradigm presented mouse data showing an immune response to its vaccine, which was enhanced by a vitamin D3 adjuvant. The DNA vaccine uses a non-viral promoter specific to muscles. The gD2 gene of the virus is delivered by the vaccine, and the promoter can only be activated in the presence of myoD protein, expressed only in muscle cells. ...