ARTICLE | Clinical News
Paradigm Biosciences Inc. preclinical data
October 28, 1996 8:00 AM UTC
Paradigm presented mouse data showing an immune response to its vaccine, which was enhanced by a vitamin D3 adjuvant. The DNA vaccine uses a non-viral promoter specific to muscles. The gD2 gene of the virus is delivered by the vaccine, and the promoter can only be activated in the presence of myoD protein, expressed only in muscle cells. ...