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Autonomic Technologies Inc., Redwood City, Calif. Product: ATI Neurostimulation System Business: Neurology Molecular target: NA Description: Miniaturized stimulator implantable at the sphenopalatine ganglion (SPG) nerve…
Published on 3/5/2012
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AVI BioPharma Inc. (NASDAQ:AVII), Bothell, Wash. Product: AVI-7288 Business: Infectious Molecular target: NA Description: Single oligomer nucleic acid analog based on morpholino-modified phosphorodiamidate oligomers (…
Published on 3/5/2012
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Intercell AG (VSE:ICLL; OTCQX:INRLY), Vienna, Austria Product: C. difficile vaccine (IC84) Business: Infectious Molecular target: NA Description: Clostridium difficile vaccine Indication: Vaccinate against C. difficile …
Published on 3/5/2012
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Baxter International Inc. (NYSE:BAX), Deerfield, Ill. Product: CD34+ stem cell therapy Business: Cardiovascular Molecular target: Not applicable Description: Autologous hematopoetic CD34+ stem cell therapy Indication: …
Published on 3/5/2012
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OncoSec Medical Inc. (OTCBB:ONCS), San Diego, Calif. Product: DNA IL-12 Business: Cancer Molecular target: Interleukin-12 (IL-12) Description: DNA plasmid coding for IL-12 delivered via electroporation Indication: Treat…
Published on 3/5/2012
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EyeGate Pharmaceuticals Inc., Waltham, Mass. Product: EGP-437 Business: Ophthalmic Molecular target: NA Description: Dexamethasone phosphate ophthalmic solution delivered by the EyeGate II Ocular Drug Delivery System …
Published on 3/5/2012
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GlobeImmune Inc., Louisville, Colo. Product: GI-6301 Business: Cancer Molecular target: NA Description: Whole, heat-killed, recombinant Saccharomyces cerevisiae yeast genetically modified (Tarmogen) to express high …
Published on 3/5/2012
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NeuroSearch A/S (CSE:NEUR), Ballerup, Denmark Product: Huntexil pridopidine (ACR16) Business: Neurology Molecular target: Dopamine receptor Description: Dopamine stabilizer Indication: Treat Huntington's disease (HD) …
Published on 3/5/2012
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Ikaria Inc., Hampton, N.J. Product: Inomax, INOflo Business: Pulmonary Molecular target: NA Description: Nitric oxide (NO) for inhalation Indication: Prevent bronchopulmonary dysplasia (BPD) Endpoint: Survival without …
Published on 3/5/2012
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Kadmon Corp. LLC, New York, N.Y. Product: KD025 Business: Autoimmune, Cancer, Neurology Molecular target: Rho-associated coiled-coil containing protein kinase 2 (ROCK2) Description: Selective Rho-associated coiled-coil …
Published on 3/5/2012
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Takeda Pharmaceutical Co. Ltd. (Tokyo:4502), Osaka, Japan Product: Leuplin leuprorelin acetate Business: Cancer Molecular target: NA Description: Analog of LH-RH Indication: Treat prostate cancer Endpoint: Suppression …
Published on 3/5/2012
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Takeda Pharmaceutical Co. Ltd. (Tokyo:4502), Osaka, Japan Product: Leuplin leuprorelin acetate Business: Cancer Molecular target: NA Description: Analog of LH-RH Indication: Treat premenopausal breast cancer Endpoint: …
Published on 3/5/2012
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Tau Therapeutics LLC, Charlottesville, Va. Product: Mibefradil Business: Cancer Molecular target: Calcium channel T-type Description: T-type calcium channel blocker Indication: Treat solid tumors Endpoint: Safety; …
Published on 3/5/2012
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Tau Therapeutics LLC, Charlottesville, Va. Product: Mibefradil Business: Cancer Molecular target: Calcium channel T-type Description: T-type calcium channel blocker Indication: Treat recurrent high grade glioma Endpoint…
Published on 3/5/2012
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Nymox Pharmaceutical Corp. (NASDAQ:NYMX), Saint-Laurent, Quebec Recordati S.p.A. (Milan:REC), Milan, Italy Product: NX-1207 Business: Genitourinary Molecular target: Undisclosed Description: Undisclosed Indication: …
Published on 3/5/2012
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Dendreon Corp. (NASDAQ:DNDN), Seattle, Wash. Product: Provenge sipuleucel-T Business: Cancer Molecular target: Not applicable Description: Autologous dendritic cells loaded with a fusion protein of prostatic acid …
Published on 3/5/2012
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Proximagen Group plc (LSE:PRX), London, U.K. Product: PRX167700 Business: Autoimmune Molecular target: Vascular adhesion protein-1 (VAP-1) (SSAO) Description: VAP-1 antagonist Indication: Treat rheumatoid arthritis (RA)…
Published on 3/5/2012
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Gilead Sciences Inc. (NASDAQ:GILD), Foster City, Calif. Product: PSI-7977, GS-7977 Business: Infectious Molecular target: HCV NS5B polymerase Description: Single isomer form of PSI-7851, a nucleotide analog HCV NS5B …
Published on 3/5/2012
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Wilex AG (Xetra:WL6), Munich, Germany Product: Rencarex girentuximab (formerly WX-G250) Business: Cancer Molecular target: Carbonic anhydrase IX (CAIX) Description: Chimeric mAb against carbonic anhydrase IX (CAIX) …
Published on 3/5/2012
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CSL Ltd. (ASX:CSL), Melbourne, Australia Product: RFVIII (CSL627) Business: Hematology Molecular target: NA Description: Recombinant coagulation single-chain factor VIII (rFVIII) Indication: Treat hemophilia A Endpoint:…
Published on 3/5/2012
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Medivir AB (SSE:MVIR B), Huddinge, Sweden Johnson & Johnson (NYSE:JNJ), New Brunswick, N.J. Product: TMC435 (formerly TMC435350) Business: Infectious Molecular target: HCV NS3/4A protease complex Description: HCV NS3/4A…
Published on 3/5/2012
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Norgine B.V., Amsterdam, the Netherlands Tranzyme Inc. (NASDAQ:TZYM), Durham, N.C. Product: Ulimorelin (TZP-101) Business: Gastrointestinal Molecular target: Ghrelin receptor (GHSR) Description: IV ghrelin receptor …
Published on 3/5/2012
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Proteonomix Inc. (OTCBB:PROT), Mountainside, N.J. Product: UMK-121 Business: Hepatic Molecular target: NA Description: Mobilization of bone marrow stem cells technology Indication: Treat end-stage liver disease (ESLD) …
Published on 3/5/2012
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Hutchison China MediTech Ltd. (LSE:HCM), Hong Kong, China AstraZeneca plc (LSE:AZN; NYSE:AZN), London, U.K. Product: Volitinib (HMPL-504) Business: Cancer Molecular target: c-Met receptor tyrosine kinase Description: …
Published on 3/5/2012
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Exelixis Inc. (NASDAQ:EXEL), South San Francisco, Calif. Kadmon Corp. LLC, New York, N.Y. Symphony Evolution Inc., Rockville, Md. Product: XL647, KD019 Business: Cancer Molecular target: Epidermal growth factor receptor…
Published on 3/5/2012