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Seattle Genetics Inc. (NASDAQ:SGEN), Bothell, Wash. Takeda Pharmaceutical Co. Ltd. (Tokyo:4502), Osaka, Japan Product: Adcetris brentuximab vedotin (SGN-35) Business: Cancer Molecular target: CD30 Description: Antibody-…
Published on 6/17/2013
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Apceth GmbH & Co. KG, Munich, Germany Product: Agenmestencel-T, MSC_apceth_101 Business: Cancer Molecular target: NA Description: Human autologous, bone-marrow derived mesenchymal stem cells Indication: Treat advanced …
Published on 6/17/2013
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AbbVie Inc. (NYSE:ABBV), Chicago, Ill. Product: Atrasentan Business: Renal Molecular target: Endothelin A receptor Description: Endothelin A receptor antagonist Indication: Treat diabetic nephropathy Endpoint: Time to …
Published on 6/17/2013
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Autifony Therapeutics Ltd., London, U.K. Product: AUT00063 Business: Other Molecular target: NA Description: Potassium channel Kv3 modulator Indication: Treat hearing loss and tinnitus Endpoint: Safety and …
Published on 6/17/2013
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BioMarin Pharmaceutical Inc. (NASDAQ:BMRN), Novato, Calif. Merck KGaA (Xetra:MRK), Darmstadt, Germany Product: BMN 165 (formerly Phenylase, PEG-PAL) Business: Endocrine/Metabolic Molecular target: NA Description: …
Published on 6/17/2013
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Cardio3 BioSciences S.A., Mont-Saint-Guibert, Belgium Product: C-Cure (C3BS-CQR-1) Business: Cardiovascular Molecular target: NA Description: Cellular therapy based on autologous stem cells differentiated into cardiac …
Published on 6/17/2013
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Concert Pharmaceuticals Inc., Lexington, Mass. Product: CTP-354 (formerly C-21191) Business: Musculoskeletal, Neurology Molecular target: GABA receptor Description: Deuterium-modified subtype-selective GABA A receptor …
Published on 6/17/2013
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Northwest Biotherapeutics Inc. (NASDAQ:NWBO), Bethesda, Md. Product: DCVax-Direct Business: Cancer Molecular target: Not applicable Description: Autologous dendritic cells designed to uptake tumor antigens in vivo …
Published on 6/17/2013
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Ascenta Therapeutics Inc., Malvern, Pa. Debiopharm Group, Lausanne, Switzerland Product: Debio 1143, AT-406 Business: Cancer Molecular target: Inhibitor of apoptosis (IAP) Description: Oral inhibitor of apoptosis (IAP) …
Published on 6/17/2013
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GlaxoSmithKline plc (LSE:GSK; NYSE:GSK), London, U.K. Product: GSK2618960 Business: Autoimmune Molecular target: Interleukin-7 (IL-7) Description: Anti-IL-7 mab Indication: Treat relapsing-remitting multiple sclerosis (…
Published on 6/17/2013
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Medicago Inc. (TSX:MDG; OTCQX:MDCGF), Quebec, Quebec Product: H5N1 VLP vaccine (Pandemic flu vaccine) Business: Infectious Molecular target: Influenza antigen Description: Plant-based virus-like particle (VLP) vaccine …
Published on 6/17/2013
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Prolor Biotech Inc. (NYSE-M:PBTH; Tel Aviv:PBTH), Ness Ziona, Israel Product: hGH-CTP (MOD-4023) Business: Endocrine/Metabolic Molecular target: NA Description: Long-acting human growth hormone (hGH) combined with the …
Published on 6/17/2013
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HemaQuest Pharmaceuticals Inc., San Diego, Calif. Product: HQK-1001 Business: Hematology Molecular target: NA Description: Oral short chain fatty acid derivative (SCFAD) Indication: Treat sickle cell disease Endpoint: …
Published on 6/17/2013
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ImmunoCellular Therapeutics Ltd. (NYSE-M:IMUC), Woodland Hills, Calif. Product: ICT-107 Business: Cancer Molecular target: Dendritic cells Description: Intradermal tumor associated antigen-pulsed dendritic cell-based …
Published on 6/17/2013
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Biota Pharmaceuticals Inc. (NASDAQ:BOTA), Rockville, Md. Daiichi Sankyo Co. Ltd. (Tokyo:4568; Osaka:4568), Tokyo, Japan Product: Inavir laninamivir octanoate (CS-8958) Business: Infectious Molecular target: …
Published on 6/17/2013
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Cerus Corp. (NASDAQ:CERS), Concord, Calif. Product: Intercept Blood System for red blood cells Business: Hematology Molecular target: DNA; RNA Description: Pathogen inactivation system using S-303 pH-activated compound …
Published on 6/17/2013
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Cerus Corp. (NASDAQ:CERS), Concord, Calif. Product: Intercept Blood System for red blood cells Business: Hematology Molecular target: DNA; RNA Description: Pathogen inactivation system using S-303 pH-activated compound …
Published on 6/17/2013
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Bioheart Inc. (OTCBB:BHRT), Sunrise, Fla. Product: LipiCell , Adipose-derived stem cells (ADSC) Business: Cardiovascular Molecular target: NA Description: Adipose-derived stem cells designed to promote angiogenesis for …
Published on 6/17/2013
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C.R. Bard Inc. (NYSE:BCR), Murray Hill, N.J. Product: Moxy Drug-Coated Balloon, Lutonix Drug Coated PTA Dilatation Catheter (DCB) Business: Cardiovascular Molecular target: Tubulin Description: Paclitaxel-coated balloon…
Published on 6/17/2013
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Naurex Inc., Evanston, Ill. Product: NRX-1074 Business: Neurology Molecular target: NMDA receptor Description: Second generation NMDA receptor modulator Indication: Treat major depressive disorder (MDD) Endpoint: Safety…
Published on 6/17/2013
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Omeros Corp. (NASDAQ:OMER), Seattle, Wash. Product: OMS721 Business: Hematology Molecular target: Mannan-binding lectin-associated serine protease-2 (MASP-2) Description: Human mAb against mannan-binding lectin-…
Published on 6/17/2013
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Puma Biotechnology Inc. (NYSE:PBYI), Los Angeles, Calif. Pfizer Inc. (NYSE:PFE), New York, N.Y. Product: Oral neratinib (HKI-272, PB272) Business: Cancer Molecular target: Epidermal growth factor receptor 1 (EGFR1) (…
Published on 6/17/2013
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Ocular Therapeutix Inc., Bedford, Mass. Product: OTX-DP, Dexamethasone-loaded punctum plug Business: Neurology Molecular target: NA Description: Hydrogel-based punctum plug that delivers sustained- and tapered-release …
Published on 6/17/2013
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PhaseBio Pharmaceuticals Inc., Morrisville, N.C. Product: PE0139 Business: Endocrine/Metabolic Molecular target: NA Description: Human monomeric long-acting basal insulin fused to an elastin-like polypeptide Indication:…
Published on 6/17/2013
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Ariad Pharmaceuticals Inc. (NASDAQ:ARIA), Cambridge, Mass. Product: Ponatinib (Iclusig) (formerly AP24534) Business: Cancer Molecular target: BCR-ABL tyrosine kinase; FMS-like tyrosine kinase 3 (FLT3) (CD135) …
Published on 6/17/2013