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Achaogen Inc., South San Francisco, Calif. Product: ACHN-975 Business: Infectious Molecular target: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (LpxC) Description: N-acetylglucosamine deacetylase (LpxC)…
Published on 5/21/2012
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AesRx LLC, Newton, Mass. Product: Aes-103 5-hydroxymethyl-2-furfural Business: Hematology Molecular target: Hemoglobin Description: Aromatic aldehyde that increases the affinity of sickle hemoglobin for oxygen …
Published on 5/21/2012
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Iroko Pharmaceuticals LLC, Philadelphia, Pa. Medicure Inc. (TSX-V:MPH; Pink:MCUJ), Winnipeg, Manitoba Merck & Co. Inc. (NYSE:MRK), Whitehouse Station, N.J. Product: Aggrastat tirofiban Business: Cardiovascular Molecular…
Published on 5/21/2012
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Cytomedix Inc. (OTCBB:CMXI), Gaithersburg, Md. Product: ALD-401 Business: Neurology Molecular target: NA Description: Stems cells derived from bone marrow expressing high levels of aldehyde dehydrogenase Indication: …
Published on 5/21/2012
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Cancer Research UK, London, U.K. Product: Curcumin Business: Cancer Molecular target: NA Description: Plant extract found in the spice turmeric Indication: Treat colorectal cancer Endpoint: Safety; efficacy as measured …
Published on 5/21/2012
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Array BioPharma Inc. (NASDAQ:ARRY), Boulder, Colo. Genentech Inc., South San Francisco, Calif. Roche (SIX:ROG; OTCQX:RHHBY), Basel, Switzerland Product: GDC-0068, RG7440 Business: Cancer Molecular target: Protein kinase…
Published on 5/21/2012
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Galapagos N.V. (Euronext:GLPG; Pink:GLPYY), Mechelen, Belgium Abbott Laboratories (NYSE:ABT), Abbott Park, Ill. Product: GLPG0634 Business: Autoimmune Molecular target: Janus kinase-1 (JAK-1) Description: Janus kinase-1…
Published on 5/21/2012
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Galectin Therapeutics Inc. (NASDAQ:GALT), Newton, Mass. Product: GM-CT-01 (formerly Davanat) Business: Cancer Molecular target: Galectin-3 (LGALS3); Galectin-1 (LGALS1) Description: Polysaccharide in a carbosome …
Published on 5/21/2012
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Biota Holdings Ltd. (ASX:BTA), Notting Hill, Australia Daiichi Sankyo Co. Ltd. (Tokyo:4568; Osaka:4568), Tokyo, Japan Product: Inavir laninamivir (CS-8958) Business: Infectious Molecular target: Neuraminidase (NEU1) (…
Published on 5/21/2012
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Juventas Therapeutics Inc., Cleveland, Ohio Product: JVS-100 Business: Cardiovascular Molecular target: Stromal cell-derived factor-1 Description: Non-viral DNA plasmid encoding stromal cell-derived factor-1 Indication:…
Published on 5/21/2012
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Helix BioPharma Corp. (TSX:HBP; NYSE-A:HBP), Aurora, Ontario Product: L-DOS47 Business: Cancer Molecular target: Not available Description: Plant-derived urease combined with a highly specialized antibody agent to …
Published on 5/21/2012
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BioAlliance Pharma S.A. (Euronext:BIO), Paris, France Product: Livatag doxorubicin Transdrug (BA-003) Business: Cancer Molecular target: DNA Description: Nanoparticle formulation of doxorubicin Indication: Treat …
Published on 5/21/2012
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AB Science S.A. (Euronext:AB), Paris, France Product: Masitinib (AB1010) Business: Cancer Molecular target: Stem cell factor (SCF) receptor tyrosine kinase (c-Kit) (KIT)(CD117) Description: Stem cell factor (SCF) …
Published on 5/21/2012
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NanoString Technologies Inc., Seattle, Wash. Product: NanoString Breast Cancer Intrinsic Subtyping Assay Business: Diagnostic Molecular target: NA Description: Breast cancer intrinsic subtyping assay that runs on the …
Published on 5/21/2012
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Promethera Biosciences S.A., Mont-Saint-Guibert, Belgium Product: Promethera HepaStem Business: Endocrine/Metabolic Molecular target: NA Description: Cell therapy of human adult liver-derived mesenchymal stem cells (…
Published on 5/21/2012
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4SC AG (Xetra:VSC), Planegg-Martinsried, Germany Yakult Honsha Co. Ltd. (Tokyo:2267), Tokyo, Japan Product: Resminostat (4SC-201) (formerly BYK408740) Business: Cancer Molecular target: Histone deacetylase (HDAC) …
Published on 5/21/2012
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Array BioPharma Inc. (NASDAQ:ARRY), Boulder, Colo. AstraZeneca plc (LSE:AZN; NYSE:AZN), London, U.K. Product: Selumetinib (AZD6244, ARRY-886) Business: Cancer Molecular target: MEK Description: Small molecule MEK …
Published on 5/21/2012
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Spectrum Pharmaceuticals Inc. (NASDAQ:SPPI), Henderson, Nev. Bayer AG (Xetra:BAYN), Leverkusen, Germany Product: Zevalin ibritumomab tiuxetan Business: Cancer Molecular target: CD20 Description: Yttrium-90-radiolabeled …
Published on 5/21/2012
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Areva Med LLC, Bethesda, Md. Product: 212Pb-TCMC-Trastuzumab Business: Cancer Molecular target: NA Description: Trastuzumab combined with lead-212 isotope Indication: Treat cancer that has metastasized the abdominal …
Published on 5/14/2012
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Achillion Pharmaceuticals Inc. (NASDAQ:ACHN), New Haven, Conn. Product: ACH-3102 Business: Infectious Molecular target: HCV NS5A protein Description: HCV NS5A protein inhibitor Indication: Treat hepatitis C virus (HCV) …
Published on 5/14/2012
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Seattle Genetics Inc. (NASDAQ:SGEN), Bothell, Wash. Takeda Pharmaceutical Co. Ltd. (Tokyo:4502), Osaka, Japan Product: Adcetris brentuximab vedotin (SGN-35) Business: Cancer Molecular target: CD30 Description: Antibody-…
Published on 5/14/2012
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Advaxis Inc. (OTCBB:ADXS), North Brunswick, N.J. Product: ADXS-HPV (ADXS11-001) (formerly Lovaxin C) Business: Cancer Molecular target: Not applicable Description: Live Listeria monocytogenes-expressing HPV type 16 E7 …
Published on 5/14/2012
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Novavax Inc. (NASDAQ:NVAX), Rockville, Md. Product: A/H5N1 Avian Influenza Vaccine Business: Infectious Molecular target: NA Description: Monovalent virus-like particle (VLP) vaccine containing hemagglutinin (HA), …
Published on 5/14/2012
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Alder Biopharmaceuticals Inc., Bothell, Wash. Product: ALD403 Business: Neurology Molecular target: Calcitonin gene-related peptide (CGRP) Description: MAb targeting calcitonin gene-related peptide (CGRP) Indication: …
Published on 5/14/2012
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Insmed Inc. (NASDAQ:INSM), Monmouth Junction, N.J. Product: Arikace (formerly SLIT amikacin) Business: Infectious Molecular target: Ribosomal 30S subunit Description: Sustained-release lipid inhaled targeting (SLIT) …
Published on 5/14/2012