Table 1. Innovation Fund award recipients. The Innovation Fund is managed by Cincinnati Children's Center for Technology Commercialization.

Source: Cincinnati Children's Center for Technology Commercialization

Principal investigator

Indication

Summary (status)

2012

 

 

John Pestian

Neurology

Markers as a predictor of repeated suicide attempts (Optioned to Assurex Health Inc.)

Margaret Hostetter

Infectious disease

Peptide vaccines and antibodies to prevent central line infections

Michael Seid; Peter Margolis

Not applicable

Collaborative chronic care (C3N) portal for personalized collaborative care (in due-diligence stage to form start up)

John Perentesis

Not applicable

Next-generation clinical trials management software

Hector Wong

Hepatic disease

Pediatric sepsis biomarker risk model (launched Persepsys Biomedical LLC in 2014 to create products that prevent death from sepsis or septic shock)

Marie-Dominique Filippi; Yi Zheng

Inflammation

Anti-inflammatory drug targeting NADPH oxidase 2 (NOX2) in acute lung injury

2013

 

 

Lee (Ted) Denson

Gastrointestinal disease

Markers to diagnose inflammatory bowel disease (IBD), Crohn's disease and ulcerative colitis (UC)

Charles Dumoulin

Imaging

Neonatal MRI scanner (in due-diligence stage to form start up)

William Hardie

Pulmonary disease

Therapy to reverse pulmonary fibrosis

Punam Malik

Hematology

Hemoglobin-g gene therapy to treat sickle cell disease

Senthil Sadhasivam

Neurology

Point-of-care gene chip to dose opioids for pain management in perioperative patients

Hector Wong

Hepatic disease

IL-27 as a biomarker for early identification of patients with sepsis

2014

 

 

Prasad Devarajan; Hermine Brunner

Autoimmune disease; renal disease

Blood test to detect the onset of kidney failure in patients with lupus

H. Leighton Grimes

Cancer

Small molecule targeting signal transducer and activator of transcription 5 (STAT5)

Michael Jordan

Autoimmune disease

Targeted, activated immune cells to suppress undesirable immune response

Ming Tan

Infectious disease

Vaccine for norovirus, rotavirus, hepatitis E virus and astrovirus