Table 1. Stand Up To Cancer awards. The charity will pay out $73.6 million over 3 years to 5 groups of cancer researchers.

 

Team leaders

 

Research focus

 

Grant ($M)

 

Craig Thompson, Abramson Cancer Center of the University of Pennsylvania;
Daniel Von Hoff, The Translational Genomics Research Institute

 

Use advanced imaging techniques to determine what nutrients pancreatic cancer cells require for growth and survival and run clinical trials designed to deprive pancreatic tumors of crucial nutrients in combination with standard chemotherapy

 

18.0

 

Joe Gray, Lawrence Berkeley National Laboratory;
Dennis Slamon, University of California, Los Angeles

 

Develop therapies for the three major subtypes of breast cancer and design a discovery platform for identifying and validating new molecular targets and breast cancer drug combinations

 

16.5

 

Lewis Cantley, Beth Israel Deaconess Medical Center;
Charles Sawyers, Memorial Sloan-Kettering Cancer Center;
Gordon Mills, The University of Texas M.D. Anderson Cancer Center

 

Use biomarkers and imaging techniques to identify breast, ovarian and endometrial cancer patients who could benefit from phosphoinositide 3-kinase (PI3K) inhibitors and develop therapeutic combinations that hit multiple targets in cellular pathways that contribute to tumor growth

 

15.0

 

Daniel Haber, Massachusetts General Hospital Cancer Center; Mehmet Toner, Harvard Medical School

 

Optimize chip technology for detecting circulating tumor cells in a large-scale clinical setting and conduct clinical trials to assess the chip's ability to detect early cancers and monitor tumor treatment response

 

15.0

 

Stephen Baylin, The Sidney Kimmel Comprehensive Cancer Center; Peter Jones, University of Southern California

 

Identify biomarkers that can predict and monitor the efficacy of epigenetic cancer therapies, develop therapies that target cancer stem cells and design a clinical trial to test the efficacy of a second-generation epigenetic anticancer compound

 

9.1

 

Total

 

 

73.6