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University of Oxford is bringing big data to translational research. The university, the U.K. government and a philanthropist are infusing up to L90 million ($138.3 million) to set up a new hub that will use large-scale…
Published on 5/23/2013
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Translational Notes: DREAM team Table 1. Sage Bionetworks-DREAM Project spring 2013 challenges. Sage Bionetworks and The DREAM Project have announced four open-innovation computational challenges that tackle issues …
Published on 5/9/2013
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The DREAM Project has teamed up with Sage Bionetworks and announced four open challenges in computational biology that tackle issues relevant to drug discovery and development. The publication of results from their …
Published on 5/9/2013
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The Structural Genomics Consortium, with grant support from the Bill & Melinda Gates Foundation, is spearheading a project to develop pharma-quality medicinal chemistry capabilities in malaria and tuberculosis. The plan…
Published on 5/9/2013
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The U.K.-based Institute of Cancer Research and Cancer Research Technology Ltd. are collaborating with Janssen to target an undisclosed step in the unfolded protein response in multiple myeloma. Previous results from …
Published on 4/18/2013
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GlaxoSmithKline today launched an academic partnering program and a $1 million cash prize to spark technology development in the new field of electroceuticals. The pharma's goal is to manipulate nerve impulses to treat …
Published on 4/11/2013
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Translational Notes: GSK goes deep with DPAc Table 1. GSK's Discovery Partnerships with Academia (DPAc) deals. Since launching the DPAc program in 2010, GlaxoSmithKline plc has partnered with nine academic teams to …
Published on 3/14/2013
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GSK's Discovery Partnerships with Academia (DPAc) program is helping the pharma cast a wide net for early stage therapeutics beyond its core areas. So far this year, GSK has struck discovery deals with Vanderbilt …
Published on 3/14/2013
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Funding breakthroughs Table 1. Founders and awardees. Founders Title(s) Science background Sergey Brin Cofounder of Google Inc. Bachelor's degree in mathematics and computer science from the University of …
Published on 3/7/2013
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Although everyone agrees that the $33 million in prize money from the Breakthrough Prize in Life Sciences Foundation went to 11 deserving scientists, it is still up for debate whether, in an age of austerity, there are …
Published on 3/7/2013
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The Brain Activity Map has been compared to the Human Genome Project; however, unlike mapping the relatively well-defined genome, the plan to visualize the brain's complete wiring scheme faces severe technical …
Published on 3/7/2013
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Six like-minded translational research centers have partnered to help speed the commercialization of academic research. The group, dubbed the Global Alliance of Leading Drug Discovery and Development Centres, comprises …
Published on 1/31/2013
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IMI's collaborative chemistry Table 1. IMI's fourth call. The fourth set of projects launched by the Innovative Medicines Initiative (IMI) comprise seven projects that are a joint effort of the European Commission …
Published on 1/24/2013
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Europe's Innovative Medicines Initiative has launched seven new public-private partnerships with a total budget of EUR237 million. In contrast to many of the organization's prior disease-focused projects, three of the …
Published on 1/24/2013
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Fred Hutchinson Cancer Research Center researchers have identified a mutation of double homeobox 4 that could be targeted in facioscapulohumeral muscular dystrophy. The team has partnered with GlaxoSmithKline to develop…
Published on 1/10/2013
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MRC Technology extends reach Table 1. MRC technology deals. Year Indication Collaborator Deal Therapeutic modality 2012 Undisclosed Shanghai Institute of Biochemistry and Cell Biology (SIBCB), part of the …
Published on 12/20/2012
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MRC Technology extends reach Table 2. Centre for Therapeutics Discovery. Target Project Stage of development Collaborator Undisclosed Undisclosed Hit to lead Undisclosed Melanocortin 3 receptor (MC3R) MC3R…
Published on 12/20/2012
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The U.K.'s Medical Research Council is taking its search for targets to Asia. The MRC's commercialization arm, MRC Technology, has announced a deal with the Shanghai Institute of Biochemistry and Cell Biology.
Published on 12/20/2012
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A shuttered AstraZeneca research center in Montreal has reemerged as Neomed, a public-private partnership between AstraZeneca, Pfizer and the government of Quebec. The institute will continue to develop AstraZeneca's …
Published on 12/13/2012
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The New York Genome Center launched its translational research unit last week with the appointment of Robert Darnell as president and scientific director. Darnell will oversee the development of internal research …
Published on 12/6/2012
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Rediscovering antibiotics Figure 1. Antibiotic approvals over the last three decades in five-year increments. In 1983-1987 the FDA approved 16 new systemic antibiotics, but since that time antibiotic approvals have …
Published on 11/29/2012
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The implementation of the Generating Antibiotic Incentives Now (GAIN) Act and other recent efforts to speed antibiotic development will only be successful if they encourage new chemical approaches that address the …
Published on 11/29/2012
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A workshop convened by the NINDS has proposed a set of standards for designing and reporting on animal studies. The challenges will be to implement the standards throughout the research community and determine which …
Published on 11/8/2012
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Translational Notes: Mess with Texas Table 1. CPRIT's commercial portfolio. The Cancer Prevention & Research Institute of Texas (CPRIT) has issued about $760 million in funding to academic researchers, community …
Published on 11/1/2012
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The recently announced oncology R&D collaboration between Sanofi and Massachusetts General Hospital takes a different tack than most translational research partnerships by starting with insights gleaned from the bedside…
Published on 11/1/2012