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Chronological Index of : Therapeutics

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  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Obesity Farnesoid X receptor (FXR; NR1H4) Mouse studies suggest FXR is required to …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Hepatic disease Cirrhosis Synoviolin (SYVN1; HRD1) Studies in human samples and mice suggest inhibiting HRD1 could …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Bacterial infection Pannexin 1 (PANX1) In vitro studies suggest avoiding PANX1 inhibition could …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Malaria Peroxisome proliferation-activated receptor-g (PPARG; PPARg) Studies in mice and human …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Meningitis; pneumonia Properdin Mouse studies suggest recombinant properdin could help protect …

    Published on 4/10/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Inflammation Inflammation Leukotriene A4 hydrolase (LTA4H) Structure-based design studies led to an LTA4H inhibitor…

    Published on 4/10/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute lymphocytic leukemia (ALL) Deoxycytidine kinase (DCK) In vitro and mouse …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute promyelocytic leukemia (APL) Retinoic acid receptor-α (RARA); promyelocytic …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer Mitogen-activated protein kinase kinase 4 (MAP2K4; MKK4) Cell …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer G protein-coupled receptor 161 (GPR161) Patient sample and cell …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Cannabinoid CB2 receptor (CNR2) In vitro and mouse studies suggest a CNR2-…

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Heat shock protein 90 (Hsp90) In vitro and mouse studies suggest a new …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer IL-23; CD40 Mouse studies suggest combination therapy with IL-23 and CD40 …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Melanoma; prostate cancer; colon cancer CTLA-4 (CD152) Mouse studies suggest …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Prostate cancer Ubiquitin specific peptidase 9 X-linked (USP9X; FAF); v-ets …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Coronary artery bypass graft (CABG) surgery Transforming growth …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Diabetes Serine/threonine kinase 4 (STK4) In vitro and mouse…

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Glycosphingolipid storage disorders Not applicable In vitro …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease HIV/AIDS HIV integrase Macaque studies suggest postcoital dosing of …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Musculoskeletal disease Musculoskeletal disease Calcium release-activated calcium channel…

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Fragile X syndrome Fragile X mental retardation 1 (FMR1) In vitro studies …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Neurology CC chemokine receptor 2 (CCR2; CD192); monocyte chemoattractant …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Stroke Phosphoinositide 3-kinase-d (PI3Kd) In vitro and mouse studies suggest …

    Published on 4/3/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Autoimmune disease Adenosine A2A receptor (ADORA2A) In vitro and …

    Published on 3/27/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute lymphoblastic leukemia (ALL) Bromodomain containing 4 (BRD4); notch 1 (…

    Published on 3/27/2014

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