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Chronological Index of : Therapeutics

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  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease HCV Cyclophilin Cell culture studies suggest nonimmunosuppressive cyclosporine-based cyclophilin…

    Published on 11/13/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Musculoskeletal disease Osteoporosis Sphingosine 1-phosphate receptor 3 (S1PR3; S1P3; EDG3); calcitonin receptor …

    Published on 11/13/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD) Sterol O-aceyltransferase 1 (SOAT1; ACAT1); b-amyloid (Ab); Ab42 Cell culture …

    Published on 11/13/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Parkinson's disease (PD) Borna disease virus p10 (BDV p10; BDV X; BDVgp1a) Mouse and cell culture studies…

    Published on 11/13/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Multiple myeloma (MM) Growth arrest and DNA-damage-inducible 45b (GADD45B); mitogen-activated protein kinase …

    Published on 11/6/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Sarcoma Sirtuin 1 (SIRT1); SIRT2 Cell culture and zebrafish studies suggest inhibiting SIRT1 could help …

    Published on 11/6/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Hypertension Forkhead box O1 (FOXO1) Studies based on patient data and rodent models suggest…

    Published on 11/6/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Thrombosis Not applicable In vitro and pig studies suggest a perfluorodecalin coating for …

    Published on 11/6/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Diabetes G protein-coupled receptor 120 (GPR120; O3FAR1) Mouse and human sample studies…

    Published on 11/6/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Hematology Transfusion Major histocompatibility complex class I A (HLA-A); HLA-B; HLA-C In vitro and mouse studies …

    Published on 11/6/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Bacterial infection Not applicable In vitro and mouse studies suggest oligosaccharide-protein …

    Published on 11/6/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Clostridium Cathelicidin antimicrobial peptide (CAMP; LL37) In vitro studies suggest nylon-3 …

    Published on 11/6/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Gram-positive bacterial infection; sepsis; Staphylococcus; Streptococcus a-hemolysin (aHL) Cell …

    Published on 11/6/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Viral infection; cytomegalovirus (CMV); Epstein-Barr virus (EBV); influenza virus CD160 In vitro…

    Published on 11/6/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Inflammation Allergy; asthma Not applicable Mouse studies suggest immunization with allergen peptides conjugated to…

    Published on 11/6/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Inflammation Asthma IL-33 (NF-HEV); tryptase In vitro and mouse studies suggest inhibiting tryptase and other IL-33…

    Published on 11/6/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Musculoskeletal disease Osteoporosis Platelet derived growth factor BB (PDGF-BB); cathepsin K (CTSK) In vitro and …

    Published on 11/6/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Neurology Notch 1 (NOTCH1) Mouse studies suggest inhibiting NOTCH1 could help treat indications involving…

    Published on 11/6/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Pulmonary disease Pulmonary disease Granulocyte macrophage colony-stimulating factor receptor (CSF2RA; GMR; CD116); …

    Published on 11/6/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer HER2 (EGFR2; ErbB2; neu); Erbb2 interacting protein (ERBB2IP; ERBIN) Cell-based, primary tumor…

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Mdm2 p53 binding protein homolog (MDM2; HDM2); p53 Mouse and in vitro studies have identified …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer MicroRNA-100 (miR-100) Cell-based, primary tumor and mouse studies suggest promoting miR-100 …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Not applicable In vitro studies suggest an osmium(vi) nitrido complex targeting cancer stem …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer AXL receptor tyrosine kinase (AXL; UFO); growth arrest-specific 6 (GAS6) In vitro and mouse studies …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Programmed cell death 1 (PDCD1; PD-1; CD279); programmed cell death 1 ligand 1 (PD-L1; B7-H1; CD274)…

    Published on 10/30/2014

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