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Indication Target/marker/pathway Summary Licensing status Publication and contact information Hematology Hemophilia Factor VIII Mouse studies suggest phosphatidylserine-bound factor VIII could help treat …
Published on 6/6/2013
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Indication Target/marker/pathway Summary Licensing status Publication and contact information Inflammation Inflammation Dendritic cell-specific ICAM-3 grabbing nonintegrin (DC-SIGN; CD209) Cell culture and …
Published on 6/6/2013
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Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD) Peripheral benzodiazepine receptor (TSPO; PBR) Mouse studies suggest TSPO …
Published on 6/6/2013
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Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Depression Protocadherin 17 (PCDH17) Mouse and nonhuman primate studies suggest inhibiting PCDH17 could …
Published on 6/6/2013
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Indication Target/marker/pathway Summary Licensing status Publication and contact information Other Progeria Isoprenylcysteine carboxyl methyltransferase (ICMT) Mouse and cell culture studies suggest …
Published on 6/6/2013
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Indication Target/marker/pathway Summary Licensing status Publication and contact information Pulmonary disease Cystic fibrosis (CF) Cystic fibrosis transmembrane conductance regulator (CFTR) In vitro and cell…
Published on 6/6/2013
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Indication Target/marker/pathway Summary Licensing status Publication and contact information Transplantation Graft-versus-host disease (GvHD) Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) …
Published on 6/6/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer Aldehyde dehydrogenase 1 family member A3 (ALDH1A3) Patient sample …
Published on 5/30/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Baculoviral IAP repeat- containing 2 (BIRC2; cIAP1); cIAP2 (BIRC3); diablo…
Published on 5/30/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Lysine-specific demethylase 4A (KDM4A; JMJD2A); jun (AP1) proto-oncogene …
Published on 5/30/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Macrophage stimulating 1 receptor c-Met-related tyrosine kinase (MST1R; RON…
Published on 5/30/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Mdm2 p53 binding protein homolog (MDM2; HDM2); p53 In vitro and mouse …
Published on 5/30/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Signal transducer and activator of transcription 3 (STAT3) In vitro and …
Published on 5/30/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Ovarian cancer Nicotinamide phosphoribosyl transferase (NAMPT; NamPRT) In vitro …
Published on 5/30/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Thrombosis Peptidyl arginine deiminase type IV (PADI4; PAD4) …
Published on 5/30/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Diabetes; obesity Not applicable Mouse studies suggest …
Published on 5/30/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Staphylococcus Accessory gene regulator cognate receptor (AgrC …
Published on 5/30/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Musculoskeletal disease Bone repair Myocilin (MYOC) Cell culture and mouse studies …
Published on 5/30/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD) Legumain (LGMN; AEP) Patient sample, tissue culture …
Published on 5/30/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Depression Not applicable Mouse studies suggest increasing ATP release from …
Published on 5/30/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Depression Serum/glucocorticoid regulated kinase 1 (SGK1) Patient, rodent and …
Published on 5/30/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Neurology Sirtuin 1 (SIRT1) In vitro and mouse studies suggest inhibiting …
Published on 5/30/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Parkinson's disease (PD) Adenosine A2A receptor (ADORA2A); monoamine oxidase B…
Published on 5/30/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Ophthalmic disease Age-related macular degeneration (AMD); retinitis PC4 and SFRS1-…
Published on 5/30/2013
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Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute myelogenous leukemia (AML) AML1-ETO oncogenic fusion protein; cyclooxygenase-2 (COX-2) In vitro and …
Published on 5/23/2013