Indication

Target/marker/pathway

Summary

Licensing status

Publication and contact information

Inflammation

Shock/trauma

Not applicable

Mouse studies suggest hemostatic nanoparticles could help treat hemorrhage following blast trauma. In a mouse model of blast trauma, 10 of 11 animals receiving i.v. hemostatic nanoparticles that contained poly(acrylic acid) survived compared with 8 of 11 mice treated with a control nanoparticle. Next steps could include validating the results in a larger number of animals.

SciBX 7(29); doi:10.1038/scibx.2014.868
Published online July 31, 2014

Patent and licensing status unavailable

Lashof-Sullivan, M.M. et al. Proc. Natl. Acad. Sci. USA; published online
June 30, 2014;
doi:10.1073/pnas.1406979111
Contact: Erin B. Lavik, Case Western Reserve University, Cleveland, Ohio
e-mail:
erin.lavik@case.edu