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Chronological Index of : Therapeutics

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  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Estrogen receptor; LYN kinase (LYN); phosphoinositide 3-kinase (PI3K) Studies in mice and …

    Published on 12/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Tripartite motif containing 37 (TRIM37) In vitro and mouse studies suggest inhibiting TRIM37 …

    Published on 12/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Cyclin dependent kinase 7 (CDK7); v-myc myelocytomatosis viral related oncogene neuroblastoma derived…

    Published on 12/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Epidermal growth factor receptor 1 (EGFR1; ErbB1; HER1); HER2 (EGFR2; ErbB2; neu); HER3 (EGFR3; ErbB3…

    Published on 12/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Globohexaosylceramide (globo-H); stage-specific embryonic antigen-3 (SSEA-3); SSEA-4 Mouse studies …

    Published on 12/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Topoisomerase II binding protein 1 (TOPBP1) Mouse and cell culture studies suggest inhibiting TOPBP1 …

    Published on 12/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Non-small cell lung cancer (NSCLC) K-Ras (KRAS) In vitro and mouse studies suggest rapamycin plus a …

    Published on 12/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Atherosclerosis Sortilin 1 (SORT1) Mouse studies suggest inhibiting SORT1 in macrophages and…

    Published on 12/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Cardiovascular disease c-jun N-terminal kinase (JNK); MAP kinase 1 (MAPK1; ERK-2); MAPK3 (…

    Published on 12/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Hypertension Angiopoietin 2 (ANG2; ANGPT2); placental growth factor (PGF; PlGF); tissue …

    Published on 12/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Ischemia/reperfusion injury Glutathione peroxidase 4 (GPX4) Mouse studies suggest …

    Published on 12/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease HIV/AIDS HIV reverse transcriptase In vitro studies have identified indolylarylsulfone …

    Published on 12/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Infectious disease IgE Mouse studies suggest enhancing persistent IgE responses could help …

    Published on 12/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Influenza virus Influenza A virus hemagglutinin Cell and mouse studies have identified …

    Published on 12/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Mycobacterium; tuberculosis VEGF receptor (VEGFR) Zebrafish studies suggest VEGFR inhibitors …

    Published on 12/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Inflammation Allergy; asthma Dermatophagoides pteronyssinus peptidase 1 (DERP1) In vitro and rat studies suggest …

    Published on 12/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Breast cancer anti-estrogen resistance 4 (BCAR4) In vitro and mouse studies suggest inhibiting…

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Liver cancer Nicotinamide adenine dinucleotide (NAD+); unconventional prefoldin RPB5 interactor (URI1; URI) …

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Lung cancer AXL receptor tyrosine kinase (AXL; UFO); discoidin domain receptor tyrosine kinase 2 (DDR2); c-…

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Melanoma BRAF; checkpoint kinase 1 (Chk1; CHEK1); Chk2 (CHEK2); ataxia telangiectasia mutated (ATM); VEGF In…

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Mesothelioma Mesothelin Mouse studies suggest intrapleural delivery of chimeric antigen receptor (CAR) T …

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Non-small cell lung cancer (NSCLC) Epidermal growth factor receptor 1 (EGFR1; HER1; ErbB1) In vitro studies …

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Aneurysm MicroRNA-24 (miR-24) Studies in patient samples and mice suggest miR-24 could help…

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Diabetes; obesity IL-22; IL-23; IL-24 (MDA7) Mouse studies suggest IL-22 or inhibition …

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Hepatic disease Liver disease Cytochrome P450 family 2 subfamily E polypeptide 1 (CYP2E1) Mouse studies suggest …

    Published on 12/11/2014

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