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Chronological Index of : Therapeutics

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  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Breast cancer anti-estrogen resistance 4 (BCAR4) In vitro and mouse studies suggest inhibiting…

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Liver cancer Nicotinamide adenine dinucleotide (NAD+); unconventional prefoldin RPB5 interactor (URI1; URI) …

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Lung cancer AXL receptor tyrosine kinase (AXL; UFO); discoidin domain receptor tyrosine kinase 2 (DDR2); c-…

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Melanoma BRAF; checkpoint kinase 1 (Chk1; CHEK1); Chk2 (CHEK2); ataxia telangiectasia mutated (ATM); VEGF In…

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Mesothelioma Mesothelin Mouse studies suggest intrapleural delivery of chimeric antigen receptor (CAR) T …

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Non-small cell lung cancer (NSCLC) Epidermal growth factor receptor 1 (EGFR1; HER1; ErbB1) In vitro studies …

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Aneurysm MicroRNA-24 (miR-24) Studies in patient samples and mice suggest miR-24 could help…

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Diabetes; obesity IL-22; IL-23; IL-24 (MDA7) Mouse studies suggest IL-22 or inhibition …

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Hepatic disease Liver disease Cytochrome P450 family 2 subfamily E polypeptide 1 (CYP2E1) Mouse studies suggest …

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Rotavirus IL-18; IL-22; toll-like receptor 5 (TLR5); NRL family CARD domain containing 4 (NLRC4)…

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Inflammation Inflammation Coiled-coil domain containing 88B (CCDC88B; CCDC88) In vitro and mouse studies suggest …

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Musculoskeletal disease Bone repair N-terminal acetyltransferase complex ARD1 subunit homolog A (NAA10; ARD1A; ARD1…

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Musculoskeletal disease Cartilage repair Piezo-type mechanosensitive ion channel component 1 (PIEZO1); PIEZO2 Cell …

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Stroke; sepsis Phosphoglycerate kinase 1 (PGK1); heat shock protein 90 (Hsp90) In vitro and rodent …

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Pulmonary disease Pulmonary disease Tumor protein 63 (TP63; p63); keratin 5 (KRT5) Mouse studies suggest distal …

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Pulmonary disease Pulmonary fibrosis Transient receptor potential vanilloid 4 (TRPV4; VRL2); transforming growth …

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Various Cardiovascular disease; liver fibrosis; pulmonary fibrosis; renal disease Glioma-associated oncogene homolog…

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Various Ischemia/reperfusion injury; renal damage Receptor-interacting serine-threonine kinase 1 (RIPK1; RIP1); …

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Various Various E3 ubiquitin ligase; SMAD specific E3 ubiquitin protein ligase 2 (SMURF2); NEDD4 family E3 …

    Published on 12/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Psoriasis IL-23 In vitro and mouse studies suggest an alphabody scaffold protein with high …

    Published on 12/4/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer Pseudomonas aeruginosa exotoxin; IL-13 receptor a2 (IL-13RA2; IL-13R; CD213A2) Engineered P. …

    Published on 12/4/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Inhibitor of k-light polypeptide gene enhancer in B cells kinase-e (IKBKE; IKKe); Janus kinase…

    Published on 12/4/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Toll-like receptor 4 (TLR4); high mobility group box 1 (HMGB1) In vitro and mouse studies suggest …

    Published on 12/4/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer V-set domain containing T cell activation inhibitor 1 (B7-H4; VTCN1) Studies in mice and patient …

    Published on 12/4/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Chronic lymphocytic leukemia (CLL) Fas apoptotic inhibitory molecule 3 (FAIM3; TOSO) In vitro and mouse …

    Published on 12/4/2014

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