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Chronological Index of : Therapeutics

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  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Multiple sclerosis (MS) BET bromodomain proteins In vitro and cell culture studies suggest …

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute myeloid leukemia (AML); B cell acute lymphoblastic lymphoma (B-ALL) Cluster of differentiation 1C (…

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer Growth factor independent 1 transcription repressor (GFI1); GFI1B In vitro and mouse studies …

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer; cancer Isocitrate dehydrogenase 1 (IDH1) Studies in patient samples and mice suggest a peptide…

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Estrogen receptor-b Studies in patient samples and mice suggest promoting phosphorylation of …

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Breast cancer 1 early onset (BRCA1) In vitro studies have identified cell-penetrant phospho-dipeptide…

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Epstein-Barr virus bhrf1 (EBV bhrf1) Cell culture and mouse studies suggest a protein-based inhibitor…

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Glycocalyx Studies in patient samples and cell culture suggest decreasing the extracellular …

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Granulocyte macrophage colony-stimulating factor (GM-CSF; CSF2); IL-4 (BSF1) Mouse studies suggest a …

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Neuroblastoma Unknown Studies in patient tissue, cell culture and mice suggest 2-O, 3-O-desulfated heparin, …

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Hypertension MicroRNA-130 (miR-130); miR-301 Studies in human samples and mice suggest …

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Obesity Not applicable Mouse studies suggest gut microbiota that express N-…

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Hematology Hematology Purinergic receptor P2Y G protein-coupled 14 (P2Y14) Mouse studies suggest agonizing P2Y14 …

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Ebola Ebola virus vp30 (vp30); protein phosphatase 1 (PPP1) Cell culture studies suggest a …

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Malaria Plasmodium falciparum apical membrane antigen 1 (ama1); P. falciparum rhoptry neck …

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Viral infection VEEVgp1 non-structural polyprotein precursor P1234 (VEEVgp1) In vitro and mouse …

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Inflammation Shock/trauma Not applicable Mouse studies suggest hemostatic nanoparticles could help treat hemorrhage…

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD) EPH receptor A4 (EPHA4); b-amyloid (Ab) Mouse studies suggest a small molecule …

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD); neurology Calpain; calpastatin Mouse studies suggest inhibiting calpain could …

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Huntington's disease (HD) p75 neurotrophin receptor (p75 NTR) Mouse studies suggest inhibiting p75 NTR …

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Pain LIM domain kinase 1 (LIMK1); LIMK2 Rat studies suggest inhibiting LIM domain kinases could help …

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Various Asthma; multiple sclerosis (MS) Galectin-9 (LGALS9); tumor necrosis factor receptor superfamily member 9 (…

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Various Cancer; inflammation BET bromodomain proteins; CREB binding protein (CREBBP; CBP); E1A binding protein p300…

    Published on 7/31/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Multiple sclerosis (MS) Granulocyte macrophage colony-stimulating factor (GM-CSF; CSF2); GM-CSF …

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute lymphoblastic leukemia (ALL) Growth differentiation factor 15 (GDF15) Mouse studies suggest inhibiting…

    Published on 7/24/2014

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