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Chronological Index of : Therapeutics

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  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Rheumatoid arthritis (RA) IL-4 (BSF1); fibronectin extra domain A (FnEDA) Mouse studies suggest …

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer c-Myc (MYC); MYC associated factor X (MAX) In vitro and mouse studies have identified compounds that …

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Epidermal growth factor receptor (EGFR) In vitro studies identified allosteric EGFR inhibitors that …

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Not applicable Rodent, canine and human studies suggest intratumoral injection of spores from the …

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Lung cancer K-Ras (KRAS); microRNA-34a (miR-34a) Mouse studies suggest nanoparticle delivery of siRNAs …

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Cardiomyopathy; heart failure Myosin heavy chain 7 cardiac muscle-b (MYH7) Mouse studies …

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Thrombosis Ectonucleoside triphosphate diphosphohydro­lase 3 (ENTPD3; CD39L3) In vitro and …

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Diabetes Forkhead box O1 (FOXO1) Mouse studies suggest FOXO1 inhibition could convert …

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Infertility Defensin b1 (DEFB1) Patient sample studies suggest increasing DEFB1 levels …

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Hepatic disease Hepatic disease Complement receptor 2 (CR2); CD59; complement C5b-9 membrane attack complex (MAC) …

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease HIV/AIDS Fc fragment of IgG receptor transporter-a (FCGRT; FCRN); HIV env Nonhuman primate …

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease HIV/AIDS Histone deacetylase (HDAC); CTLA-4 (CD152); BET bromodomain proteins; HIV env Mouse …

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease HIV/AIDS HIV gp120; HIV gp41 Studies in human serum samples suggest broadly neutralizing …

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Musculoskeletal disease Muscular dystrophy Dysferlin (DYSF) Studies in patients suggest proteasome inhibitors could…

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Musculoskeletal disease Osteoporosis Wingless-type MMTV integration site family member 4 (WNT4) Mouse studies …

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD) Protein tyrosine phosphatase non-receptor type 5 (PTPN5; STEP) In vitro and …

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Amyotrophic lateral sclerosis (ALS) Chromosome 9 open reading frame 72 (C9orf72) In vitro studies suggest…

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Parkinson's disease Calcineurin; a-synuclein (SNCA) Cell culture and animal studies suggest calcineurin …

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Rett syndrome DNA (cytosine-5-)-­ methyltransferase 1 (DNMT1); 3-phosphoinositide dependent protein …

    Published on 9/11/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute lymphoblastic leukemia (ALL) Leukemia-induced noncoding activator RNA (LUNAR1); insulin-like growth …

    Published on 9/4/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer Galectin-1 (LGALS1) Rodent studies suggest inhibiting LGALS1 could help treat brain tumors. …

    Published on 9/4/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer DEAD box polypeptide 20 (DDX20; DP103) Studies in patient samples, mice and cell culture …

    Published on 9/4/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Cathepsin S Studies in patient samples and mice suggest inhibiting cathepsin S could help prevent …

    Published on 9/4/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Fibroblast growth factor receptor (FGFR); IL-6; JAK kinase (JAK); phosphoinositide 3-kinase (PI3K); …

    Published on 9/4/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Focal adhesion kinase (FAK) Mouse studies suggest endothelial cell-specific inhibition of FAK could …

    Published on 9/4/2014

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