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Chronological Index of : Therapeutics

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  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Multiple sclerosis (MS) Granulocyte macrophage colony-stimulating factor (GM-CSF; CSF2); GM-CSF …

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute lymphoblastic leukemia (ALL) Growth differentiation factor 15 (GDF15) Mouse studies suggest inhibiting…

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer RAS oncogene family member RAB22A In vitro and mouse studies suggest inhibiting RAB22A could …

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Adrenergic receptor b3 (ADRB3) Studies in patient samples and mice suggest protecting nestin-positive…

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer BET bromodomain proteins; smoothened (SMO) Mouse and cell culture studies suggest BET bromodomain …

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer c-Myc (MYC); plasmacytoma variant translocation 1 oncogene (PVT1) Studies in patient samples and cell…

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Endometrial cancer Protein phosphatase methylesterase 1 (PPME1) In vitro, primary tumor and mouse studies …

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Pancreatic cancer G protein-coupled receptor 81 (GPR81) Cell-based, patient sample and mouse studies suggest…

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Obesity Adenosine A2B receptor (ADORA2B); kruppel-like factor 4 (KLF4; EZF) Mouse and …

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Hepatic disease Liver disease High mobility group box 1 (HMGB1) Studies in patient samples and mice suggest …

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease HCV Acyl-CoA synthetase long-chain family member 1 (ACSL1) Cell culture studies suggest …

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Malaria Not applicable In vitro and mouse studies have identified a new class of antiparasitic …

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Sepsis Aryl hydrocarbon receptor (AHR); indoleamine 2,3-dioxygenase 1 (IDO1) Mouse studies …

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Skin and skin structure infection (SSSI) Staphylococcus accessory gene regulator A (agrA) In …

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Inflammation Inflammatory disease Inducible T cell kinase (ITK) In vitro and in vivo studies have identified a …

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Pain Angiotensin II type 2 receptor (ATGR2) In vitro and mouse studies suggest agonizing ATGR2 could help…

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Pain Neurotrophic tyrosine kinase receptor 1 (NTRK1; TrkA) In vitro and rat studies identified small …

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Ophthalmic disease Glaucoma ATPase Na+/K+ transporting a2 polypeptide (ATP1A2) In vitro and rabbit studies have …

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Pulmonary disease Chronic obstructive pulmonary disease (COPD) Integrin aVb8 Mouse and in vitro studies suggest an …

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Renal disease Renal disease Centrosomal protein 290 kDa (CEP290) Mouse and cell culture studies suggest hedgehog …

    Published on 7/24/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Various Cancer; thrombosis Plasminogen activator inhibitor 1 (SERPINE1; PAI1) In vitro and mouse studies suggest …

    Published on 7/24/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Inflammatory bowel disease (IBD) IL-9 Studies in human samples and …

    Published on 7/17/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute lymphoblastic leukemia (ALL) Cyclin dependent kinase 7 (CDK7) In vitro and …

    Published on 7/17/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer B cell lymphoma B cell lymphoma 2 (BCL-2; BCL2); cyclin dependent kinase 4 (CDK4…

    Published on 7/17/2014
  • Therapeutics

    This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Neuromedin U (NMU); HER2 (EGFR2; ErbB2; neu) Cell culture and mouse…

    Published on 7/17/2014

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