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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Autoimmune CD4; CD52; sialic acid binding Ig-like lectin 10 (SIGLEC10)…
Published on 6/13/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Multiple sclerosis (MS) Ciliary neurotrophic factor (CNTF) In vitro …
Published on 6/13/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Osteoarthritis (OA) Transforming growth factor b1 (TGFb1; TGFB1); TGFb…
Published on 6/13/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Interleukin-6 (IL-6); interleukin-8 (IL-8; CXCL8) Mouse and cell …
Published on 6/13/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Histone deacetylase 6 (HDAC6); histone deacetylase 8 (HDAC8) In vitro …
Published on 6/13/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Nuclear receptor subfamily 5 group A member 2 (NR5A2; LRH-1) Mouse and in …
Published on 6/13/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Phosphodiesterase d subunit (PDEd); Ras Mouse studies suggest inhibiting …
Published on 6/13/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Colon cancer p53 Mouse and cell culture studies suggest gain-of-function …
Published on 6/13/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Melanoma Pyruvate dehydrogenase kinase 1 (PDK1) Cell culture and mouse studies …
Published on 6/13/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Sarcoma Sphingosine 1-phosphate (S1P); S1P receptor 1 (S1PR1; S1P1; EDG1) Cell …
Published on 6/13/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Infertility Phosphoinositide 3-kinase (PI3K); phosphatase and…
Published on 6/13/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Bacterial infection; candidiasis; malaria Poly-N-acetylglucosamine (…
Published on 6/13/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Bacterial infection Toll-like receptor 2 (TLR2); CD14 Patient sample…
Published on 6/13/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Pain Adenylate cyclase 1 (ADCY1; AC1); NMDA receptor NR2B subtype (GRIN2B; NR2B…
Published on 6/13/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Parkinson's disease (PD) a-Synuclein (SNCA) In vitro fruit fly and mouse …
Published on 6/13/2013
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This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Transplantation Transplant Thrombopoietin (TPO) receptor (CD110; Mpl) Mouse studies …
Published on 6/13/2013
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Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Epidermal growth factor receptor 3 (EGFR3; HER3; ErbB3); HER2 (EGFR2; ErbB2; neu) Patient sample and …
Published on 6/6/2013
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Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Integrin a4b1 (CD49D/CD29) Human and mouse studies suggest inhibiting integrin a4b1 could help …
Published on 6/6/2013
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Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Poliovirus receptor-related 4 (PVRL4) In vitro and mouse studies suggest inhibiting PVRL4 could help …
Published on 6/6/2013
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Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Thrombospondin-1 (TSP-1; THBS1); prosaposin (PSAP) Cell-based and mouse studies suggest increasing …
Published on 6/6/2013
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Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Tumor necrosis factor receptor 1 (TNFRSF1A; TNFR1; CD120a) A study in mice suggests decreasing …
Published on 6/6/2013
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Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Chronic lymphocytic leukemia (CLL) RAD51 homolog (RAD51); activation-induced cytidine deaminase (AICDA; AID)…
Published on 6/6/2013
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Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Melanoma VEGF receptor 2 (KDR/Flk-1; VEGFR-2) Mouse studies suggest co-delivery of engineered T cells …
Published on 6/6/2013
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Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Cardiomyopathy; heart failure Growth differentiation factor 11 (GDF11) Studies in mice …
Published on 6/6/2013
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Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Diabetes Fatty acid binding protein 4 adipocyte (FABP4) In vitro and mouse studies …
Published on 6/6/2013