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Chronological Index of : Therapeutics

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  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer HER2 (EGFR2; ErbB2; neu); Erbb2 interacting protein (ERBB2IP; ERBIN) Cell-based, primary tumor…

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Mdm2 p53 binding protein homolog (MDM2; HDM2); p53 Mouse and in vitro studies have identified …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer MicroRNA-100 (miR-100) Cell-based, primary tumor and mouse studies suggest promoting miR-100 …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Not applicable In vitro studies suggest an osmium(vi) nitrido complex targeting cancer stem …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer AXL receptor tyrosine kinase (AXL; UFO); growth arrest-specific 6 (GAS6) In vitro and mouse studies …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Programmed cell death 1 (PDCD1; PD-1; CD279); programmed cell death 1 ligand 1 (PD-L1; B7-H1; CD274)…

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Zinc finger CCCH-type antiviral 1 (ZC3HAV1; ZAP) In vitro and mouse studies suggest an oncolytic …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Arrhythmia Purkinje cell protein 4 (PCP4) Mouse studies suggest agonizing PCP4 could help …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Obesity Not applicable Mouse studies suggest the mitochondria-targeted coenzyme Q10 …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Bacterial infection; Enterococcus Enterococcus faecalis endocarditis and biofilm-associated pilus…

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Pneumococcus Not applicable Cell culture and mouse studies suggest Streptococcus pneumoniae …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Inflammation Inflammation CXC chemokine receptor 1 (CXCR1); CXCR2 (IL8RB) In vitro and mouse studies suggest a new …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Musculoskeletal disease Musculoskeletal disease SMAD family member 1 (MADH1; SMAD1) MADH5 (SMAD5); MADH9 (SMAD9; …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Musculoskeletal disease Musculoskeletal disease Wingless-type MMTV integration site family member 16B (WNT16B) …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD) Legumain (LGMN; AEP); microtubule-associated protein-t (MAPT; tau; FTDP-17) In …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Epilepsy Not applicable In vitro and rodent studies suggest analogs of octanoic acid could help treat …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Neuroinflammation High mobility group box 1 (HMGB1); HMGB2 Cell culture and mouse studies have identified…

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Pain k-opioid receptor (OPRK1; KOR) Mouse studies suggest the G protein-biased KOR agonists could help …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Various Tissue damage; ischemia/reperfusion injury; infectious disease Unknown Mouse and flatworm studies have …

    Published on 10/30/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Osteoarthritis Matrix metalloproteinase 13 (MMP13) In vitro and rat studies identified selective…

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer Spermidine/spermine-N1-acetyltransferase 1 (SAT1; SSAT) Studies in patients, mice and cell …

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer AT rich interactive domain 1A (ARID1A); ARID1B; breast cancer 1 early onset (BRCA1); BRCA2; K-Ras (…

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Dermcidin (DCD) Cell culture studies suggest the Serinicoccus-derived natural compound seriniquinone …

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Protein disulfide isomerase (PDI) Cell culture studies suggest PDI inhibitors could sensitize cancers…

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Chronic lymphocytic leukemia (CLL) Lymphotoxin-a (LTa); lymphotoxin-b receptor (LTBR); chemokine CXC motif …

    Published on 10/23/2014

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