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Chronological Index of : Techniques

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  • Techniques

    Approach Summary Licensing status Publication and contact information Drug platforms Small molecule inhibitors of microRNA processing An in vitro screening system could be used to identify small molecule …

    Published on 4/10/2014
  • Techniques

    This week in techniques Approach Summary Licensing status Publication and contact information Disease models Bioluminescent mouse model of HPV+ oral tumors to track the effect of therapeutics A bioluminescent …

    Published on 4/3/2014
  • Techniques

    This week in techniques Approach Summary Licensing status Publication and contact information Disease models Mouse model of dominant Ullrich congenital muscular dystrophy (UCMD) A mouse model of dominant UCMD …

    Published on 4/3/2014
  • Techniques

    This week in techniques Approach Summary Licensing status Publication and contact information Drug delivery Engineered, zinc finger domain-containing recombinases for site-specific delivery of therapeutic genes…

    Published on 4/3/2014
  • Techniques

    This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Crystal structure of metabotropic glutamate receptor subtype 1 (mGluR1; GRM1) The crystal structure …

    Published on 4/3/2014
  • Techniques

    This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Hexamer-forming mAbs that activate the complement system mAbs engineered with mutations that promote …

    Published on 4/3/2014
  • Techniques

    This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Mouse cardiomyocytes generated from fibroblasts with one pluripotency factor and four small molecules…

    Published on 4/3/2014
  • Techniques

    This week in techniques Approach Summary Licensing status Publication and contact information Imaging Multiplexed ion beam imaging (MIBI) for detection of up to 100 target proteins in clinical samples Imaging …

    Published on 4/3/2014
  • Techniques

    This week in techniques Approach Summary Licensing status Publication and contact information Markers Fluorescent antibodies to membrane-bound tumor necrosis factor (mTNF) as a predictive biomarker for …

    Published on 4/3/2014
  • Techniques

    This week in techniques Approach Summary Licensing status Publication and contact information Assays & screens Cell-based prediction of the fraction of free, unbound compound in brain tissue A high throughput, …

    Published on 3/27/2014
  • Techniques

    This week in techniques Approach Summary Licensing status Publication and contact information Chemistry Hydrophobic cross-linking of peptides to create inhibitors of protein-protein interactions Hydrophobic …

    Published on 3/27/2014
  • Techniques

    This week in techniques Approach Summary Licensing status Publication and contact information Chemistry Synthetic low molecular weight heparins (LMWHs) with reversible and high anticoagulation activity …

    Published on 3/27/2014
  • Techniques

    This week in techniques Approach Summary Licensing status Publication and contact information Computational models Rational design platform to generate dual-acting kinase and bromodomain inhibitors In vitro …

    Published on 3/27/2014
  • Techniques

    This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Functional, expandable human hepatocytes obtained by direct reprogramming Two studies suggest …

    Published on 3/27/2014
  • Techniques

    This week in techniques Approach Summary Licensing status Publication and contact information Markers Morning cortisol and self-reported depression symptoms to predict risk of major depressive disorder in …

    Published on 3/27/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Assays & screens Plasma lipid signature to identify presymptomatic individuals that may progress to Alzheimer's disease (AD) Clinical data …

    Published on 3/20/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Assays & screens Telomerase promoter activity-based assay to detect circulating tumor cells (CTCs) An adenovirus that expresses GFP from the …

    Published on 3/20/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Disease models A hepatoma-based cell culture model that supports the entire cycle of HBV and HCV Cell culture studies suggest a hepatoma-…

    Published on 3/20/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Drug platforms Bispecific, diagnostic antibodies for enhanced detection of dimerized or phosphorylated oncoproteins Cell culture studies …

    Published on 3/20/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Drug platforms Müller glia cells as a source for regenerative retinal neuronal cell types In vitro and mouse studies suggest Müller glia …

    Published on 3/20/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Markers Cerebrospinal fluid (CSF) levels of soluble CD19 to detect CNS disease in patients with lymphoma Human sample studies suggest …

    Published on 3/20/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Markers Circulating giant macrophages as diagnostic markers for metastasizing tumors Human sample studies suggest detection of circulating …

    Published on 3/20/2014
  • Techniques

    This week in techniques Approach Summary Licensing status Publication and contact information Assays & screens Measurement of b-amyloid (Ab) oligomers in cerebrospinal fluid (CSF) to diagnose and monitor the …

    Published on 3/13/2014
  • Techniques

    This week in techniques Approach Summary Licensing status Publication and contact information Assays & screens Protein M, an IgG-binding protein with a new mode of antibody interaction In vitro studies suggest …

    Published on 3/13/2014
  • Techniques

    This week in techniques Approach Summary Licensing status Publication and contact information Disease models Long-term, Plasmodium cynomolgi-infected primary hepatocyte culture to screen for malaria therapeutics…

    Published on 3/13/2014

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