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Chronological Index of : Techniques

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  • Techniques

    Approach Summary Licensing status Publication and contact information Drug platforms Crystal structure of the b-ketoacyl reductase (KR) domain of fatty acid synthase (FASN; FAS)-small molecule inhibitor complex …

    Published on 9/4/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Drug platforms Glial Schwann cell precursors as a source for dental stem cells Mouse studies suggest glia cell precursors could be developed …

    Published on 9/4/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Markers Circulating microRNA signature to diagnose acetaminophen poisoning An 11-miRNA signature could be used to identify acetaminophen …

    Published on 9/4/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Markers Excision repair cross-complementation group 2 (ERCC2) mutations as a predictive marker of cisplatin sensitivity in urothelial …

    Published on 9/4/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Assays & screens High-coverage, single-cell genome and exome sequencing at base-pair resolution to aid biomarker identification A single-cell…

    Published on 8/28/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Disease models Single immunoglobulin and toll-interleukin 1 receptor domain (Sigirr; Tir8)-deficient mouse model of Campylobacter jejuni …

    Published on 8/28/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Drug delivery Targeting glioma stem-like cells (GSCs) with CpG-siRNA conjugates Cell culture and mouse studies suggest CpG-siRNA-conjugated …

    Published on 8/28/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Drug platforms Chimeric antigen receptor (CAR)-specific invariant NK T (iNKT) cell therapy CAR-specific iNKT cell therapies could be designed…

    Published on 8/28/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Drug platforms Oncolytic virus to enhance efficacy of chimeric antigen receptor (CAR)-specific T cells Mouse studies suggest oncolytic …

    Published on 8/28/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Drug platforms X-ray crystal structures of thiol-reactive agents in complex with Mycobacterium tuberculosis secreted antigen 85-C (fbpC; ag85C…

    Published on 8/28/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Markers Integrated genomic and proteomic analysis of cancer cells to prioritize the study of cancer drivers Combined genomic and proteomic …

    Published on 8/28/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Markers RAC1 P29S as a marker of resistance to BRAF inhibitors in melanoma Mouse and cell culture studies suggest RAC1 P29S could be useful …

    Published on 8/28/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Assays & screens Genomewide screen for identifying barriers to generation of human induced pluripotent stem (iPS) cells A screen to identify …

    Published on 8/21/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Assays & screens Gold plasmonic chip for biomarker discovery and diagnosis of type 1 diabetes An islet antigen microarray on a gold plasmonic…

    Published on 8/21/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Assays & screens Immunosignature diagnosis platform Immunosignature profiles could be used to diagnose or classify various human diseases. A …

    Published on 8/21/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Chemistry Asparagine-aspartate peptide ligase for peptide macrocyclization An asparagine-aspartate ligase, butelase 1, could enable the …

    Published on 8/21/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Chemistry Guidelines for the design of orally available macrocycles A set of guidelines derived from an analysis of structures of macrocycles…

    Published on 8/21/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Computational models Computational prediction of loops at protein-protein interfaces using LoopFinder A computational approach to predict …

    Published on 8/21/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Disease models Calmodulin binding transcription activator 1 (Camta1)-deficient mice as a model of ataxia and neurodegenerative disease Camta1…

    Published on 8/21/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Drug platforms Creation of biological pacemaker from ventricular myocytes A gene therapy approach to create a temporary biological pacemaker …

    Published on 8/21/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Drug platforms HIV genome excision from host cells using guide RNA (gRNA)-directed Cas9 genome editing In vitro studies suggest gRNA-directed…

    Published on 8/21/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Imaging 3D, carbonized polyacrylonitrile scaffolds to promote bone tissue regeneration 3D, carbonized polyacrylonitrile scaffolds could be …

    Published on 8/21/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Markers Gastric tumor classification system Studies in patient samples have identified a classification system for human gastric cancers that…

    Published on 8/21/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Assays & screens EnPlex, a high throughput flow cytometry platform to assess potency and selectivity of small molecule enzyme inhibitors The …

    Published on 8/14/2014
  • Techniques

    Approach Summary Licensing status Publication and contact information Assays & screens One-bead, one-compound peptoid-encoded a-helix mimetic library to identify chaperones or inhibitors of protein-protein …

    Published on 8/14/2014

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