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Approach Summary Licensing status Publication and contact information Assays & screens High throughput sequencing of tumor tissue to guide clinical trial enrollment High throughput sequencing of tumor tissue …
Published on 1/5/2012
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Approach Summary Licensing status Publication and contact information Assays & screens Quantification of minimal residual disease in chronic lymphocytic leukemia (CLL) following hematopoietic stem cell transplant…
Published on 1/5/2012
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Approach Summary Licensing status Publication and contact information Assays & screens Real-time classification of glioma tumors with mass spectrometry-based lipid profiling A mass spectrometry-based method for …
Published on 1/5/2012
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Approach Summary Licensing status Publication and contact information Chemistry Selective arylation of imidazoles to synthesize Tasigna nilotinib and its analogs N1-selective palladium-catalyzed arylation of …
Published on 1/5/2012
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Approach Summary Licensing status Publication and contact information Drug platforms Prophylactic vaccination with antibody-expressing adenoviral transgenes An adenoviral vector encoding pathogen-neutralizing …
Published on 1/5/2012
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Approach Summary Licensing status Publication and contact information Chemistry High throughput identification of chiral oligomers of pentenoic amides (COPAs) as protein ligands Screening libraries of COPAs …
Published on 12/15/2011
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Approach Summary Licensing status Publication and contact information Chemistry Photocatalytic redox method for incorporating trifluoromethyl (CF3) groups into drug compounds A method of chemical synthesis …
Published on 12/15/2011
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Approach Summary Licensing status Publication and contact information Drug platforms Chemical-genetic interaction networks for target discovery against methicillin-resistant Staphylococcus aureus (MRSA) …
Published on 12/15/2011
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Approach Summary Licensing status Publication and contact information Drug platforms Mammalian cell-based discovery of high-affinity human antibodies from IgG libraries A human cell line-based platform could be…
Published on 12/15/2011
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Approach Summary Licensing status Publication and contact information Drug platforms Rational design of glycoconjugate vaccines Glycoconjugate vaccines that maximize the presentation of carbohydrate-specific T …
Published on 12/15/2011
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Approach Summary Licensing status Publication and contact information Imaging Topically applied, tumor-activated fluorescence probe for ovarian cancer biopsy and resection A topically applied, tumor-activated …
Published on 12/15/2011
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Approach Summary Licensing status Publication and contact information Markers Metabolomic signature for metastatic colon cancer prognosis A patient study identified an NMR signature that could help determine …
Published on 12/15/2011
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Approach Summary Licensing status Publication and contact information Disease models K-Ras-mutant, cyclin dependent kinase inhibitor 2A (Cdkn2a; Ink4a; Arf; p16ink4a)-deficient mouse cell model of sarcoma Mouse …
Published on 12/8/2011
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Approach Summary Licensing status Publication and contact information Drug platforms Trypanosoma cruzi expressing cancer/testis antigen 1B (CTAG1B; NY-ESO-1) as an anticancer vaccine vector A highly attenuated T…
Published on 12/8/2011
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This week in techniques Approach Summary Licensing status Publication and contact information Assays & screens A targeted sequencing method to identify genetic alterations in fixed tumor samples Targeted …
Published on 12/1/2011
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This week in techniques Approach Summary Licensing status Publication and contact information Assays & screens A yeast functional screen for identifying amyotrophic lateral sclerosis (ALS) genes A yeast …
Published on 12/1/2011
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This week in techniques Approach Summary Licensing status Publication and contact information Assays & screens Single-cell PCR analysis of tumor samples to identify prognostic gene expression signatures A …
Published on 12/1/2011
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This week in techniques Approach Summary Licensing status Publication and contact information Computational models Automated quantification of breast cancer morphology features in microscopic images for …
Published on 12/1/2011
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This week in techniques Approach Summary Licensing status Publication and contact information Drug delivery Poly(n-butyl cyanoacrylate) dextran polymers coated with polysorbate 80 (PBCA nanoparticles) for brain …
Published on 12/1/2011
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This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms An improved protocol to derive dopaminergic neurons from embryonic stem cells (ESCs) to treat …
Published on 12/1/2011
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This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Embryonic stem cell (ESC)-derived anterior pituitary tissues for treating endocrine diseases In vitro…
Published on 12/1/2011
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This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Engineered pancreatic islets Engineered pancreatic islets could help lower rejection risk in patients…
Published on 12/1/2011
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This week in techniques Approach Summary Licensing status Publication and contact information Chemistry Gram-scale preparation of paclitaxel precursors for synthesis of taxane analogs Gram-scale synthesis of …
Published on 11/17/2011
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This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Target-specific, near-infrared photoimmunotherapy to treat cancer Mouse studies suggest near-infrared…
Published on 11/17/2011
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This week in techniques Approach Summary Licensing status Publication and contact information Instrumentation Intra-arterial catheter for in vivo microstructural and molecular imaging Tissue sample and rabbit …
Published on 11/17/2011