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This week in techniques Approach Summary Licensing status Publication and contact information Computational models Algorithm for chemical space exploration with stochastic search (ACSESS) to develop structurally…
Published on 5/2/2013
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This week in techniques Approach Summary Licensing status Publication and contact information Disease models Frog model for scoliosis A frog model for scoliosis caused by ear damage could be useful for studying…
Published on 5/2/2013
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This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Chimeric antigen receptor (CAR)-expressing T cells lacking negative regulators of T cell receptor (TCR…
Published on 5/2/2013
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This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Fibroblast-derived induced oligodendrocyte progenitor cells (iOPCs) to treat myelination disorders …
Published on 5/2/2013
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This week in techniques Approach Summary Licensing status Publication and contact information Imaging Functional MRI (fMRI) to monitor psychosis Mouse and human studies suggest fMRI could be useful for …
Published on 5/2/2013
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This week in techniques Approach Summary Licensing status Publication and contact information Markers Brown adipose tissue (BAT) in adult humans Two separate studies in humans identified physiological and …
Published on 5/2/2013
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Approach Summary Licensing status Publication and contact information Chemistry Semisynthetic synthesis of artemisinin Biological production of artemisinic acid and chemical conversion of the acid to artemisinin…
Published on 4/25/2013
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Approach Summary Licensing status Publication and contact information Chemistry Simplified synthesis of pactamycin to aid analog development A simplified process for pactamycin synthesis could facilitate the …
Published on 4/25/2013
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Approach Summary Licensing status Publication and contact information Disease models Mouse model for collagen type VI a3 (COL6A3)-related muscular dystrophies A mouse model for COL6A3-related muscular …
Published on 4/25/2013
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Approach Summary Licensing status Publication and contact information Disease models Mouse models for neurological disease controlled with cellular-scale optogenetic brain implants Mice with cellular-scale …
Published on 4/25/2013
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Approach Summary Licensing status Publication and contact information Drug platforms Antitumor mechanism of gold nanoparticles in ovarian cancer Mouse and cell culture studies suggest gold nanoparticles could be…
Published on 4/25/2013
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Approach Summary Licensing status Publication and contact information Drug platforms Clustered, regularly interspaced short palindromic repeats (CRISPR) editing to rapidly generate stem cell models for disease A…
Published on 4/25/2013
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Approach Summary Licensing status Publication and contact information Drug platforms Highly potent inhibitors of sirtuin 1 (SIRT1), SIRT2 and SIRT3 Thieno[3,2-d]pyrimidine-6-carboxamide-based sirtuin inhibitors …
Published on 4/25/2013
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Approach Summary Licensing status Publication and contact information Drug platforms Transplantable kidney graft from a decellularized kidney extracellular matrix (ECM) A transplantable kidney built on a …
Published on 4/25/2013
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Approach Summary Licensing status Publication and contact information Drug platforms Using chromatin immunoprecipitation followed by whole-genome sequencing (ChIP-Seq) to identify disease-associated super-…
Published on 4/25/2013
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Approach Summary Licensing status Publication and contact information Imaging Optical imaging of structural and molecular features in intact brain tissue A method of rendering intact brain tissue amenable to …
Published on 4/25/2013
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Approach Summary Licensing status Publication and contact information Markers Fibroblast growth factor receptor (FGFR) fusions associated with multiple cancer types Patient sample and mouse studies identified …
Published on 4/25/2013
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Approach Summary Licensing status Publication and contact information Chemistry Generation of high-affinity DNA aptamers using non-natural nucleotides Non-natural nucleotides could be useful for generating high-…
Published on 4/18/2013
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Approach Summary Licensing status Publication and contact information Disease models In vitro 3D biomimetic model for angiogenic sprouting An in vitro biomimetic model for angiogenic sprouting could be useful …
Published on 4/18/2013
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Approach Summary Licensing status Publication and contact information Drug delivery Integrin avb3 (CD51/CD61)-targeting nanoparticles for retinal capillary endothelial cell drug delivery In vitro and mouse …
Published on 4/18/2013
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Approach Summary Licensing status Publication and contact information Drug platforms Optimizing antigen affinity in T cell tumor vaccines Cell culture and mouse studies suggest strong T cell receptor (TCR) …
Published on 4/18/2013
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Approach Summary Licensing status Publication and contact information Drug platforms Rational design of HIV gp120 immunogen to induce broadly neutralizing antibodies HIV gp120 immunogen complexes could be used …
Published on 4/18/2013
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Approach Summary Licensing status Publication and contact information Imaging High-performance liquid chromatography (HPLC)-single-crystal diffraction (SCD) analysis to guide drug development HPLC-SCD analysis …
Published on 4/18/2013
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This week in techniques Approach Summary Licensing status Publication and contact information Assays & screens Panel of peptoid ligands of aquaporin-4 (AQP4) autoantibodies for diagnosing neuromyelitis optica (…
Published on 4/11/2013
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This week in techniques Approach Summary Licensing status Publication and contact information Assays & screens Yeast chemical genetic screen for inhibitors of human telomerase A yeast chemical genetic screening…
Published on 4/11/2013