Table 1. 2012 CIRM grants. Research grants awarded by the California Institute for Regenerative Medicine (CIRM) to develop stem cell-based therapies.

Source: CIRM

Lead Institution

Lead principal
investigator

CIRM funding ($M)

Proposal summary

Cedars-Sinai Medical Center

Clive Svendsen

17.8

Treat amyotrophic lateral sclerosis (ALS) using progenitor cells secreting glial cell-derived neurotrophic factor (GDNF)

Stanford University

Robert Robbins

20.0

Treat end-stage heart failure using embryonic stem cell (ESC)-derived cardiomyocytes

Stanford University

Judith Shizuru

20.0

Develop a method for chemotherapy-free bone marrow transplants (BMTs) in severe combined immunodeficient (SCID) patients using an antibody that targets blood cell-forming stem cells

StemCells Inc.

Nobuko Uchida

20.0

Treat cervical spinal cord injury (SCI) using neural stem cells

University of California, Davis

John Laird

14.2

Treat critical limb ischemia using intramuscular injection of VEGF-producing mesenchymal stem cells (MSCs)

UC Davis

Nancy Lane

20.0

Treat osteoporosis using endogenous MSCs

UC Davis

Vicki Wheelock

19.0

Treat Huntington's disease (HD) using bone marrow-derived MSCs engineered to produce brain-derived neurotrophic factor (BDNF)

University of California, Los Angeles

Antoni Ribas

20.0

Treat melanoma using stem cells engineered to express melanoma-specific T cell receptors (TCRs)

Total

 

151.0