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Chronological Index of : Therapeutics

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  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute lymphoblastic leukemia (ALL) MEK; notch 1 (NOTCH1); phosphoinositide 3-kinase (PI3K) Mouse and cell …

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute myelogenous leukemia (AML) CD3; C-type lectin domain family 12 member A (CLEC12A; CLL1) Studies in …

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer g-aminobutyric acid A receptor-p (GABRP) In vitro studies suggest inhibiting GABRP could help …

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Butyrophilin subfamily 3 member A1 (BTN3A1) Cell culture studies suggest a pivaloyloxymethyl-…

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Casein kinase 1a (CSNK1A; CKI-a); sonic hedgehog homolog (SHH) Mouse and cell culture studies suggest…

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer DNA Mouse studies have identified a class of platinum(iv) complexes that could be useful for treating…

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Lung cancer ADAM9; CUB domain containing protein 1 (CDCP1) Studies in patient samples and mice suggest …

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Mantle cell lymphoma (MCL) Phosphoinositide 3-kinase (PI3K); cyclin dependent kinase 4 (CDK4); Bruton's …

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Melanoma BRAF; epidermal growth factor receptor 3 (EGFR3; HER3; ERBB3) Cell culture and mouse studies …

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Prostate cancer Androgen receptor (AR) Cell culture studies have identified AR-inhibiting 4-(4-phenylthiazol…

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Cardiomyopathy; heart failure Hydroxyeicosapentaenoic acid (18-HEPE) Mouse studies suggest …

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Cardiomyopathy; heart failure Serine/threonine kinase 3 (STK3; MST2) Studies in human …

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Thrombosis Factor Xa; thrombin (factor IIa; F2); factor IXa; factor VIIa/tissue factor …

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Diabetes Islet amyloid polypeptide (IAPP) In vitro and mouse studies suggest enhancing …

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Hematology Stem cell transplant Ret proto-oncogene (RET) In vitro and mouse studies suggest RET agonists could …

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Inflammation Asthma Helicobacter pylori g-glutamyl transpeptidase (ggt); H. pylori vacuolating cytotoxin (vacA) …

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Amyotrophic lateral sclerosis (ALS) Prostaglandin D2 receptor subtype DP1 (PTGDR1; DP1); superoxide …

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Pulmonary disease Cystic fibrosis (CF) Cystic fibrosis transmembrane conductance regulator (CFTR) Cell culture …

    Published on 8/28/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Fatty acid synthase (FASN; FAS) Mouse studies suggest inhibiting FASN could help prevent tumor …

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Guanine nucleotide binding protein q polypeptide (GNAQ; Gaq); MAS-related GPR member X1 (MRGPRX1; …

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Stem cell factor receptor tyrosine kinase (c-Kit; KIT; CD117) In vitro studies have identified …

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Liver cancer Prolactin (PRL); PRL receptor (PRLR) In vitro and mouse studies suggest increasing PRL …

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Melanoma; breast cancer; cancer Adenosine A2A receptor (ADORA2A); CTLA-4 (CD152); ecto-5ʹ-nucleotidase (NT5E;…

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Prostate cancer Androgen receptor (AR); prostate-specific antigen (KLK3; PSA) In vitro studies have …

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Prostate cancer Lysine-specific demethylase 4A (KDM4A; JMJD2A); KDM4B (JMJD2B) Cell culture studies suggest…

    Published on 8/21/2014

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