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Chronological Index of : Therapeutics

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  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer DNA (cytosine-5-)-methyltransferase 1 (DNMT1) Cell culture studies have identified non-nucleoside …

    Published on 11/20/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Fibroblast growth factor receptor (FGFR) In vitro studies suggest covalent, ATP-competitive FGFR …

    Published on 11/20/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Nuclear factor (erythroid-derived 2)- like 2 (NFE2L2; NRF2); K-RAS (KRAS) Mouse and cell culture …

    Published on 11/20/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Colorectal cancer Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1; CD66a); hepatitis A …

    Published on 11/20/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Neuroendocrine tumors Arginase 1 (ARG1); GABAA receptor In vitro and mouse studies suggest inhibiting ARG1 …

    Published on 11/20/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Intimal hyperplasia Interferon regulatory factor 9 (IRF9); sirtuin 1 (SIRT1) Mouse studies …

    Published on 11/20/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Ischemia/reperfusion injury N-methylpurine-DNA glycosylase (MPG; APNG; AAG) Mouse studies …

    Published on 11/20/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Myocardial infarction (MI) Stem cell factor (SCF; c-Kit ligand; KITLG) Porcine studies …

    Published on 11/20/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Bacterial infection DNA gyrase subunit B (gyrB); topoisomerase IV Par E subunit (parE) Rodent …

    Published on 11/20/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Pneumococcus; pneumonia Endothelial cell nitric oxide synthase 3 (NOS3; eNOS) Mouse studies …

    Published on 11/20/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Musculoskeletal disease Muscular dystrophy Latent transforming growth factor-b binding protein 4 (LTBP4) Mouse …

    Published on 11/20/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Amyotrophic lateral sclerosis (ALS) Adducin 1 (ADD1); ATPase Na+/K+ transporting a2 polypeptide (ATP1A2) …

    Published on 11/20/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Neurology; Parkinson's disease (PD) MAP kinase kinase kinase 12 (MAP3K12; DLK) In vitro and mouse studies…

    Published on 11/20/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Psychosis; schizophrenia Dopamine D3 receptor; serotonin (5-HT1A) receptor; serotonin (5-HT2A) receptor …

    Published on 11/20/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Renal disease Renal damage Transient receptor potential cation channel subfamily M member 2 (TRPM2); Ras-related C3…

    Published on 11/20/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Bladder cancer Bone morphogenetic protein 4 (BMP4); BMP5; smoothened (SMO) Mouse studies suggest activating …

    Published on 11/13/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer; lung cancer PDZ binding kinase (PBK; TOPK) Mouse studies suggest a selective TOPK inhibitor …

    Published on 11/13/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Epidermal growth factor receptor 3 (EGFR3; HER3; ErbB3) In vitro studies identified a bivalent, ATP-…

    Published on 11/13/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Phosphoinositide 3-kinase (PI3K); PI3K class 3 (Vps34) In vitro studies have identified the small …

    Published on 11/13/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Toll-like receptor 4 (TLR4); HPV antigens; survivin (BIRC5) Mouse studies suggest a combination of …

    Published on 11/13/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Ischemia/reperfusion injury p53 Mouse studies suggest activating p53 in cardiac fibroblasts …

    Published on 11/13/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Diabetes; obesity Ceramide synthase 6 (CERS6; LASS6) In vitro and mouse studies suggest…

    Published on 11/13/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Obesity Adenosine A2A receptor (ADORA2A) Mouse studies suggest ADORA2A agonists could …

    Published on 11/13/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Obesity; metabolic disease Estrogen receptor-a; peroxisome proliferation-activated …

    Published on 11/13/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Bacterial infection Ixodes scapularis antifreeze glycoprotein (iafgp); poly-N-acetyl glucosamine…

    Published on 11/13/2014

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