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Zaltrap, aflibercept, ziv-aflibercept

Also known as: VEGF Trap (AVE0005)

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Company Regeneron Pharmaceuticals Inc.
DescriptionFusion protein containing the extracellular domains from 2 VEGF receptors linked to the Fc portion of human IgG
Molecular Target Vascular endothelial growth factor (VEGF) ; Placental growth factor (PGF) (PlGF)
Mechanism of ActionVascular endothelial growth factor (VEGF) inhibitor
Therapeutic ModalityBiologic: Fusion protein

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Disease CategoryStandard IndicationIndication DetailsPartnersMilestonesLatest Stage of DevelopmentRegulatory Designation
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