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Rencarex, girentuximab (formerly WX-G250)

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Company Wilex AG
DescriptionChimeric mAb against carbonic anhydrase IX (CAIX)
Molecular Target Carbonic anhydrase IX (CAIX)
Mechanism of ActionAntibody; Antibody dependent cellular cytotoxicity (ADCC)
Therapeutic ModalityBiologic: Antibody
Latest Stage of DevelopmentPhase III
Standard IndicationRenal cancer
Indication DetailsTreat clear cell renal cell carcinoma (RCC); Treat non-metastatic clear cell renal cell carcinoma (ccRCC); Treat renal cancer
Regulatory Designation

U.S. - Fast Track (Treat clear cell renal cell carcinoma (RCC));
U.S. - Orphan Drug (Treat renal cancer);
EU - Orphan Drug (Treat renal cancer)


Esteve S.A.

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