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Vivitrol, naltrexone

Also known as: XR-NTX (formerly Medisorb naltrexone, Vivitrex)

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Company Alkermes plc
DescriptionInjectable sustained-release formulation of naltrexone in polylactide co-glycolide polymer microspheres
Molecular Target Opioid receptor (OPR)
Mechanism of ActionOpioid receptor antagonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationAddiction
Indication DetailsPrevent relapse to opioid dependence; Treat alcohol and opiate addiction; Treat alcohol and opiate dependence; Treat alcohol dependence; Treat opiate addiction; Treat opioid dependence; Treat opioid-using adults not physically dependent on opioids
Regulatory Designation U.S. - Priority Review (Treat opioid dependence)
PartnerJohnson & Johnson

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