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Vistide, cidofovir (GS 504)

Also known as: Forvade

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Company Gilead Sciences Inc.
DescriptionTopical small molecule nucleotide analog
Molecular Target Viral polymerase
Mechanism of ActionViral polymerase inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationCytomegalovirus (CMV)
Indication DetailsPrevent progression of cytomegalovirus (CMV) infection of the peripheral retina in AIDS patients; Treat bone marrow transplant (BMT) recipients at risk for cytomegalovirus (CMV) infection; Treat cytomegalovirus (CMV) retinitis in patients with AIDS; Treat relapsing cytomegalovirus (CMV) infection of the retina in AIDS; Treat relapsing cytomegalovirus (CMV) retinitis; Treatment of peripheral retinitis due to cytomegalovirus (CMV) in AIDS patients; Untreated cytomegalovirus (CMV) infection of the retina in AIDS
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