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ombitasvir/paritaprevir/ritonavir/dasabuvir (Viekira XR)

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Company AbbVie Inc.
DescriptionOnce-daily, extended-release, co-formulation of ombitasvir, an HCV NS5A protein inhibitor; paritaprevir, an HCV NS3/4A protease inhibitor; ritonavir, an HIV protease inhibitor; and dasabuvir, a non-nucleoside HCV NS5B polymerase inhibitor
Molecular Target HCV NS3/4A protease complex ; HCV NS5A protein
Mechanism of ActionHIV protease inhibitor; HCV non-structural protein 5A inhibitor; HCV non-structural protein 5B inhibitor; HCV NS3 protease inhibitor
Therapeutic ModalitySmall molecule: Combination
Latest Stage of DevelopmentApproved
Standard IndicationHepatitis C virus (HCV)
Indication DetailsTreat chronic HCV genotype 1 infection with and without compensated cirrhosis
Regulatory Designation
PartnerEnanta Pharmaceuticals Inc.

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