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Victrelis, boceprevir (MK-3034) (formerly SCH 503034)

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Company Merck & Co. Inc.
DescriptionSmall molecule HCV NS3/4A protease inhibitor
Molecular Target HCV NS3/4A protease complex
Mechanism of ActionViral protease inhibitor
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationHepatitis C virus (HCV)
Indication DetailsTreat chronic HCV genotype 1 infection; Treat chronic HCV genotype 1 infection in combination with standard of care in adults with compensated liver disease who are treatment naïve or have failed treatment; Treat chronic HCV genotype 1 infection in patients who failed prior therapy; Treat chronic HCV genotype 1 infection in patients who failed prior therapy and treatment-naïve patients; Treat chronic HCV genotype 1 infection in treatment-naïve patients; Treat patients co-infected with HCV and HIV
Regulatory Designation

U.S. - Fast Track (Treat chronic HCV genotype 1 infection);
EU - Accelerated Assessment (Treat chronic HCV genotype 1 infection)

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