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imilecleucel-T (Tcelna) (formerly Tovaxin)

Also known as: T-cell vaccine

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Company Opexa Therapeutics Inc.
DescriptionPatient-specific myelin reactive T cells (MRTCs) primed and expanded ex vivo with myelin-associated peptides
Molecular Target T cell receptor (TCR)
Mechanism of ActionVaccine
Therapeutic ModalityActive immunotherapy
Latest Stage of DevelopmentPhase II
Standard IndicationMultiple sclerosis (MS)
Indication DetailsTreat multiple sclerosis (MS); Treat secondary progressive multiple sclerosis (SPMS)
Regulatory Designation U.S. - Fast Track (Treat secondary progressive multiple sclerosis (SPMS))
Partner Merck KGaA

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