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Vocimagene amiretrorepvec (Toca 511)

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Company Tocagen Inc.
DescriptionRetroviral replicating vector delivering the gene encoding cytosine deaminase (CD), an enzyme that converts prodrug 5-fluorocytosine (5-FC) into active form 5-fluorouracil (5-FU)
Molecular Target
Mechanism of ActionGene therapy
Therapeutic ModalityGene therapy: Viral vector
Latest Stage of DevelopmentPhase I
Standard IndicationBrain cancer
Indication DetailsTreat recurrent high-grade glioma
Regulatory Designation

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