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THR-184

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Collapse Summary General Information
Company Thrasos Therapeutics Inc.
DescriptionSmall peptide that selectively activates activin receptor-like kinase 2 (ALK2; ACVR1) and ALK3
Molecular Target Activin receptor-like kinase 2 (ALK2) (ACVR1) ; Activin receptor-like kinase 3 (ALK3)
Mechanism of Action 
Therapeutic ModalityPeptide
Latest Stage of DevelopmentPhase II
Standard IndicationRenal damage
Indication DetailsPrevent acute kidney injury (AKI) in patients undergoing cardiac surgery; Treat acute kidney injury (AKI) post-surgery
Regulatory Designation

U.S. - Fast Track (Prevent acute kidney injury (AKI) in patients undergoing cardiac surgery)

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