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axelopran (TD-1211)

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Company Theravance Biopharma Inc.
DescriptionOral peripheral mu opioid receptor antagonist
Molecular Target Mu opioid receptor (OPRM1) (MOR)
Mechanism of ActionMu opioid receptor antagonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentPhase II
Standard IndicationConstipation
Indication DetailsTreat opioid-induced constipation (OIC)
Regulatory Designation

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