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Targretin, bexarotene

Also known as: Targretin Capsules, Targretin Gel (LGD1069, LGD1268, LGD1324)

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Company Eisai Co. Ltd.
DescriptionOral selective retinoid X receptor (RXR) modulator; insulin sensitizer
Molecular Target Retinoid X receptor (RXR)
Mechanism of ActionRetinoid X receptor (RXR) agonist
Therapeutic ModalitySmall molecule
Latest Stage of DevelopmentMarketed
Standard IndicationCutaneous T cell lymphoma (CTCL)
Indication DetailsTreat advanced stage cutaneous T cell lymphoma (CTCL); Treat cutaneous lesions in patients with early-stage cutaneous T cell lymphoma (CTCL); Treat cutaneous T cell lymphoma (CTCL); Treat early and advanced cutaneous T cell lymphoma (CTCL); Treat early-stage cutaneous T cell lymphoma (CTCL); Treat mycosis fungoides (cutaneous T cell lymphoma (CTCL)); Treat stage I/IIA cutaneous T cell lymphoma ((CTCL) mycosis fungoides)
Regulatory Designation

Japan - Orphan Drug (Treat cutaneous T cell lymphoma (CTCL))

Partner

Minophagen Pharmaceutical Co. Ltd.; Valeant Pharmaceuticals International Inc.


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