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Synribo, Omacetaxine mepesuccinate (formerly Ceflatonin, Omapro)

Also known as: sHHT (formerly CGX-635, homoharringtonine)

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Collapse Summary General Information
Company Teva Pharmaceutical Industries Ltd.
DescriptionSmall molecule that targets the ribosome to inhibit synthesis of oncoproteins
Molecular Target Cyclin D1 (CCND1) (BCL1) ; Myeloid leukemia cell differentiation protein (MCL1)
Mechanism of ActionMyeloid leukemia cell differentiation protein (Mcl-1) inhibitor
Latest Stage of DevelopmentApproved
IndicationChronic myelogenous leukemia (CML)
Partner

Hospira Inc.
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