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Stemgen, ancestim (Stem cell factor)

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Company Swedish Orphan Biovitrum AB
DescriptionRecombinant form of stem cell factor (SCF)
Molecular Target Stem cell factor (SCF) receptor tyrosine kinase (c-Kit) (KIT) (CD117)
Mechanism of ActionStem cell factor (SCF) receptor tyrosine kinase (c-Kit) (KIT) (CD117) agonist
Therapeutic ModalityBiologic
Latest Stage of DevelopmentMarketed
Standard IndicationStem cell transplant
Indication DetailsAdjuvant to Neupogen filgrastim-mediated mobilization prior to autologous peripheral blood progenitor cell transplantation; Increase blood stem cells in cancer patients
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